1315378-72-3
Post Buying Request-
-
Basic information
- Product Name: Scrambled 10Panx
- Synonyms: Scrambled 10Panx
- CAS NO:1315378-72-3
- Molecular Formula: C58H79N15O16
- Molecular Weight: 1242.36
- EINECS: N/A
- Product Categories: peptides
- Mol File: 1315378-72-3.mol
- Article Data: 0
-
Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: ≥31.05 mg/mL in DMSO
- CAS DataBase Reference: Scrambled 10Panx(CAS DataBase Reference)
- NIST Chemistry Reference: Scrambled 10Panx(1315378-72-3)
- EPA Substance Registry System: Scrambled 10Panx(1315378-72-3)
-
Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1315378-72-3(Hazardous Substances Data)
1315378-72-3 Suppliers
Recommended suppliersmore
1315378-72-3 Usage
Biological Activity
scrambled 10panx is the scrambled form of 10panx (wrqaafvdsy), a mimetic peptide of pannexin 1 that inhibits dye uptake by macrophages without affecting cellular membrane currents. being structurally similar to anther peptide panxe1b, 10panx is three amino acid shorter but exerting an inhibitory effect against pannexin1 currents in oocytes to a similar extent as panxe1b. 10panx is also able to block the activation of i2nd, decrease the bradykinin-induced [ca2+]i response and attenuate bradykinin-induced atp release from human fibroblasts loaded with quinacrine. however, in several studies, scrambled 10panx has been proved to be less effective than 10panx in its authentic form.roger j. thompson, michael f. jackson, michelle e. olah, ravi l. rungta, dustin j. hines, michael a. beazely, john f. macdonald, brian a. macvicar. activation of pannexin-1 hemichannels augments aberrant bursting in the hippocampus. science 2008; 322: 1555-1559.ana rita pinheiro, diogo paramos-de-carvalho, marianna certal, cristina costa, maria teresa magalhaes-cardoso, fatima ferreirinha, maria adelina costa and paulo correia-de-sa. bradykinin-induced ca2+ signaling in human subcutaneous fibroblasts involves atp release via hemichannels leading to p2y12 receptors activation. communication and signaling 2013, 11:70junjie wang, meiyun ma, silviu locovei, robert w. keane and gerhard dahl. modulation of membrane channel currents by gap junction protein mimetic peptides: size matters. am j physiol cell physiol 293: c1112-c1119, 2007Check Digit Verification of cas no
The CAS Registry Mumber 1315378-72-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,5,3,7 and 8 respectively; the second part has 2 digits, 7 and 2 respectively.Calculate Digit Verification of CAS Registry Number 1315378-72:
(9*1)+(8*3)+(7*1)+(6*5)+(5*3)+(4*7)+(3*8)+(2*7)+(1*2)=153
153 % 10 = 3
So 1315378-72-3 is a valid CAS Registry Number.
1315378-72-3Upstream product
1315378-72-3Downstream Products
Post a RFQ
1
What can I do for you?
Get Best Price
Get Best Price for 1315378-72-3
Scrambled 10Panx
