1315380-84-7Relevant academic research and scientific papers
Catalytic asymmetric hydrogenation of heterocyclic ketone-derived hydrazones, pronounced solvent effect on the inversion of configuration
Haddad, Nizar,Qu, Bo,Rodriguez, Sonia,Van Der Veen, Lars,Reeves, Diana C.,Gonnella, Nina C.,Lee, Heewon,Grinberg, Nelu,Ma, Shengli,Krishnamurthy, Dhileepkumar,Wunberg, Tobias,Senanayake, Chris H.
supporting information; experimental part, p. 3718 - 3722 (2011/08/06)
An enantioselective hydrogenation of hydrazones derived from heterocyclic ketones was developed with up to 85% ee. The enantiomeric purity was enriched to >99% ee by crystallization from EtOAc in >80% yield. Optimization studies have revealed a notable so
