131540-59-5Relevant academic research and scientific papers
Structure-activity relationships of a series of novel (piperazinylbutyl)thiazolidinone antipsychotic agents related to 3-[4-[4-(6- fluorobenzo[b]thien-3-yl)-1-piperazinyl]butyl]-2,5,5-trimethyl-4- thiazolidinone maleate
Hrib, Nicholas J.,Jurcak, John G.,Bregna, Deborah E.,Burgher, Kendra L.,Hartman, Harold B.,Kafka, Sharon,Kerman, Lisa L.,Kongsamut, Sam,Roehr, Joachim E.,Szewczak, Mark R.,Woods-Kettelberger, Ann T.,Corbett, Roy
, p. 4044 - 4057 (2007/10/03)
HP-236 (3-[4-[4-(6-Fluorobenzo[b]thien-3-yl)-1-piperazinyl]butyl]- 2,5,5-trimethyl-4-thiazolidinone maleate; P-9236) (54) displayed a pharmacological profile indicative of potential atypical antipsychotic activity. A series of piperazinyl butyl thiazolidi
3-[4-(1-substituted-4-piperazinyl)butyl]-4-thiazolidinone and related compounds
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, (2008/06/13)
There are disclosed compounds of the formula, STR1 where n is 0, 1 or 2; A is STR2 where X in each occurrence is independently hydrogen, halogen, loweralkyl, hydroxy, nitro, loweralkoxy, amino, cyano, trifluoromethyl or methylthio; Y in each occurrence is
3-[4-(1-Substituted-4-piperazinyl)butyl]-4-thiazolidinone compounds
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, (2008/06/13)
3-[4-1-substituted-4-piperazinyl)butyl]-4-thiazolidinone compounds which are useful as antipsychotic, analgesic, anticonvulsant and anxiolytic agents.
