131544-23-5Relevant academic research and scientific papers
Palladium-catalyzed cascade 5-exo-trigradical cyclization/aromatic C-H alkylation with unactivated alkyl iodides
Sun, Xi,Dong, Xu,Yang, Yi,Fu, Jiangchen,Wang, Yan,Li, Zirui,Liu, Yuying,Liu, Hui
, p. 2676 - 2680 (2021)
A novel and convenient palladium-catalyzed cascade 5-exo-trigradical cyclization/aromatic C-H alkylation with unactivated alkyl iodides has been described. This strategy provides an efficient access to a variety of 3a-methyl-1,2,3,3a,4,8b-hexahydroindeno[1,2-b]pyrrole derivatives, which facilitate access to a series of medically important heterocyclic bioactive molecules. This protocol involves mild catalytic reaction conditions and shows high functional group tolerance with high stereoselectivity. Mechanistic investigations reveal that an alkyl radical pathway is involved in this reaction.
Diverse reactivity in a rhodium(III)-catalyzed oxidative coupling of N-allyl arenesulfonamides with alkynes
Wang, Dongqi,Wang, Fen,Song, Guoyong,Li, Xingwei
supporting information, p. 12348 - 12352 (2013/02/23)
Olefinic CiH activation of N-allyl sulfonamides in the presence of [{RhCpCl2}2] (Cp=Me5C5) enabled their oxidative coupling with alkynes to generate 1,2-dihydropyridines, pyridines, and cyclopentenones (see scheme; Ts=p-toluenesulfonyl). The type of highly substituted product formed was controlled by the substitution of the allyl group and the reaction conditions. Copyright
Manipulation of Substrate-Controlled Diastereoselectivities in Hydroborations in Acyclic Allylamine Derivatives
Burgess, Kevin,Ohlmeyer, Michael J.
, p. 1027 - 1036 (2007/10/02)
Racemic, and optically active, 2-methyl-3-(N-tosylamino)alkenes I were prepared and subjected to both catalyzed and uncatalyzed hydroborations.Data obtained for the catalyzed hydroborations of these allylamine derivatives are consistent with the theory of
