131545-66-9Relevant academic research and scientific papers
Perfluorinated analogues of poison ivy allergens. Synthesis and skin tolerogenic activity in mice
Fraginals,Schaeffer,Stampf,Benezra
, p. 1024 - 1027 (1991)
3-(Tridecafluoroundecyl)catechol (8) and 3-(nonafluoropentadecyl)catechol (9), perfluorinated analogues of pentadecylcatechol (PDC), a constituent of poison ivy, have been synthesized. These compounds were nonsensitizers in mice. Compounds 8 and 9, however, were elicitors of allergic contact dermatitis in PDC-sensitized animals. Moreover, compound 9 exhibited tolerogenic properties to sensitization by poison ivy allergens, i.e. mice pretreated with perfluorinated compounds could not be sensitized to PDC.
