1315480-44-4Relevant academic research and scientific papers
New investigation of Vilsmeier-type reaction using pyrazolones with various amides
Huang, Yu-Ying,Kaneko, Kimiyoshi,Takayama, Hiroyuki,Kimura, Masayuki,Wong, Fung Fuh
supporting information; experimental part, p. 3786 - 3792 (2011/08/06)
New investigation of Vilsmeier-type reaction was evaluated to realize the solvent effect by using pyrazolones to react with various of amides, including formamide, N-methylformamide, N-propylformamide, N-tert-butylformamide, N,N-dimethylformamide (DMF), N,N-diethylformamide (DEF), N,N-dipropylformamide (DPF), N,N-diisopropylformamide, N,N-dibutylformamide, piperidine-1- carbaldehyde, and pyrrolidine-1-carbaldehyde, in the presence of phosphorous oxychloride POCl3. The unexpected resulting products were observed in this work according to the difference chemoseletivities of substituted amides. The plausible reactive pathways were proposed to explain the experimental result. Crown Copyright
