1315573-24-0

Basic information

• Product Name: 4'-[5-(benzyloxycarbonylaminomethyl)-3-propyl-1,2,4-triazol-1-ylmethyl]biphenyl-2-carboxylic acid t-butyl ester
• Synonyms: 4'-[5-(benzyloxycarbonylaminomethyl)-3-propyl-1,2,4-triazol-1-ylmethyl]biphenyl-2-carboxylic acid t-butyl ester
• CAS NO: 1315573-24-0
• Molecular Weight: 540.662
• Mol File: 1315573-24-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4'-[5-(benzyloxycarbonylaminomethyl)-3-propyl-1,2,4-triazol-1-ylmethyl]biphenyl-2-carboxylic acid t-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-[5-(benzyloxycarbonylaminomethyl)-3-propyl-1,2,4-triazol-1-ylmethyl]biphenyl-2-carboxylic acid t-butyl ester(1315573-24-0)
• EPA Substance Registry System: 4'-[5-(benzyloxycarbonylaminomethyl)-3-propyl-1,2,4-triazol-1-ylmethyl]biphenyl-2-carboxylic acid t-butyl ester(1315573-24-0)

Safety Data

• Hazardous Substances Data: 1315573-24-0(Hazardous Substances Data)

Upstream product

• 1206697-02-0 (5-propyl-4H-1,2,4-triazol-3-ylmethyl)carbamic acid benzyl ester 
• 114772-40-6 4'-bromomethyl-biphenyl-2-carboxylic acid tert-butyl ester 

Relevant articles and documents

DUAL-ACTING ANTIHYPERTENSIVE AGENTS

In one aspect, the invention relates to compounds having the formula: wherein: Ar, r, Z, X, R3, and R5-7 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.