131575-76-3

Upstream product

• 131575-72-9 1-(3,4-methylenedioxyphenyl)-2-phenylsulphonylethyne 
• 99528-63-9 (2S,3R)-2,3-epoxy-3-phenylpropan-1-ol 
• 57134-53-9 3,4-methylenedioxyphenylethyne 
• 120-57-0 piperonal 
• 1504-58-1 3-Phenyl-2-propyn-1-ol 
• 4510-34-3 (Z)-cinnamyl alcohol 
• 92449-54-2 5-(2,2-dibromovinyl)-1,3-benzodioxol 
• 131575-70-7 1-bromo-1-(3,4-methylenedioxyphenyl)-2-phenylsulphonylethene 
• 536-74-3 phenylacetylene 
• 2297-65-6 benzenesulfonyl bromide 

Downstream Products

• 131575-78-5 (4R,αS)-4-(α-hydroxybenzyl)-2-(3,4-methylenedioxyphenyl)-3-phenylsulphonyl-4,5-dihydrofuran 

Relevant academic research and scientific papers

Approaches to 2,6-Diaryl-3,7-DioxabicycloOctane Lignans via Asymmetric Synthesis of Dihydro- and Tetrahydro-furan Derivatives

Cyclisation of chiral non-racemic phenylsulphonylvinyl epoxy ethers, produced using the Sharpless epoxidation reaction, has been used to prepare a series of enantiomerically enriched 2-aryl-4-(α-hydroxybenzyl)-4,5-dihydrofuran derivatives.Reduction of these compounds using triethylsilane and BF3-diethyl ether gave the corresponding tetrahydrofuran derivatives stereoselectively.Attempts to convert either the dihydro- or tetrahydro-furan derivatives into lignans belonging to the 2,6-diaryl-3,7-dioxabicyclooctane series so far proved unsuccessful.