13159-78-9Relevant academic research and scientific papers
Green and scalable aldehyde-catalyzed transition metal-free dehydrative N-alkylation of amides and amines with alcohols
Xu, Qing,Li, Qiang,Zhu, Xiaogang,Chen, Jianhui
supporting information, p. 73 - 80 (2013/03/13)
In contrast to the borrowing hydrogen-type N-alkylation reactions, in which alcohols were activated by transition metal-catalyzed anaerobic dehydrogenation, the addition of external aldehydes was accidentally found to be a simple and effective protocol for alcohol activation. This interesting finding subsequently led to an efficient and green, practical and scalable aldehyde-catalyzed transition metal-free dehydrative N-alkylation method for a variety of amides, amines, and alcohols. Mechanistic studies revealed that this reaction most possibly proceeds via a simple but interesting transition metal-free relay race mechanism. Copyright
Synthesis and microbiological evaluations of (N-heteroaryl)arylmethanamines and their Schiff bases
Fioravanti,Biava,Donnarumma,Porretta,Simonetti,Villa,Porta-Puglia,Deidda,Maullu,Pompei
, p. 643 - 652 (2007/10/03)
The synthesis as well as the antimicrobial and antiviral activities of new (N-heteroaryl)arylmethanamines and their Schiff bases are reported. None of the tested compounds showed activity against Herpes simplex virus type 2 and against Gram positive and Gram negative bacteria. Weak or moderate activity on poliovirus Sabin type 1, on reverse transcriptase and against Cryptococcus neoformans was shown by some of the tested compounds. Viceversa several synthesized compounds exhibited a moderate or good activity against strains of Candida albicans, while only some of the tested compounds were found moderately active against strains of Candida sp. Instead numerous new compounds 3 or 4 were active as control against isolates of plant pathogenic fungi. The obtained results are discussed on the basis of structure-activity relationships.
Fungicidal amines
-
, (2008/06/13)
N,N-Disubstituted heterocyclic amines are useful as fungicides.
