1316098-49-3Relevant academic research and scientific papers
3,4-Dihydroxypyrrolidines via modified tandem aza-payne/hydroamination pathway
Kulshrestha, Aman,Salehi Marzijarani, Nastaran,Dilip Ashtekar, Kumar,Staples, Richard,Borhan, Babak
, p. 3592 - 3595 (2012)
The outcome of a tandem aza-Payne/hydroamination reaction is modified via the use of a latent nucleophile. The latter initially serves as an electrophile to intercept the aziridine alkoxide and afterward turns into a nucleophile thereby performing the aziridine ring opening, out competing the intramolecular aza-Payne pathway. Subsequent hydroamination in the same pot provides N-Ts enamide carbonates, which can be easily converted into biologically significant 3,4-dihydroxylactams.
Catalytic asymmetric aziridination of α,β-unsaturated aldehydes
Deiana, Luca,Dziedzic, Pawel,Zhao, Gui-Ling,Vesely, Jan,Ibrahem, Ismail,Rios, Ramon,Sun, Junliang,Cordova, Armando
supporting information; experimental part, p. 7904 - 7917 (2011/08/05)
The development, scope, and application of the highly enantioselective organocatalytic aziridination of α,β-unsaturated aldehydes is presented. The aminocatalytic azirdination of α,β-unsaturated aldehydes enables the asymmetric formation of β-formyl aziri
