1316194-31-6

Basic information

• Product Name: C₂₅H₁₆N₄O₂S
• CAS NO: 1316194-31-6
• Molecular Weight: 436.494
• Mol File: 1316194-31-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₅H₁₆N₄O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₅H₁₆N₄O₂S(1316194-31-6)
• EPA Substance Registry System: C₂₅H₁₆N₄O₂S(1316194-31-6)

Safety Data

• Hazardous Substances Data: 1316194-31-6(Hazardous Substances Data)

Upstream product

• 486-25-9 9-fluorenone 
• 1316194-27-0 2-(9H-fluoren-9-ylidene)-2-mercaptoacetic acid 
• 882-32-6 p-chlorophenylazomalononitrile 
• 1316194-23-6 5-(9H-fluoren-9-ylidene)-2-thioxo-4-thiazolidinone 

Relevant articles and documents

Synthesis, theoretical study, and antimicrobial activity of novel polysubstituted thiazoles

New 5-(9H-Fluoren-9-ylidene)-and 5-(1H-indan-1-ylidene)-2-thioxo-4- thiazolidinones 3a, b were synthesized Eco-friendly under microwave irradiation (MWI). These compounds undergo alkaline hydrolysis to afford the corresponding thiol derivatives 4a, b, which cyclized into polysubstituted thiazoles 6a-h using arylazomalononitriles 5a-d as nucleophilic agents. Some selected products were tested for their antimicrobial activities. The equilibrium geometries of the studied compounds were calculated at the B3LYP/6-31G(d) level of the density functional theory (DFT). Conformational analysis has been carried out to determine the most stable conformers. The relative stability of the azo and hydrazo tautomers has been investigated. The HOMO-LUMO energy gap is used in rationalizing the reactivity of the studied compounds. The Japan Institute of Heterocyclic Chemistry.