1316227-82-3Relevant academic research and scientific papers
Highly enantioselective yttrium(III)-catalyzed Friedel-Crafts alkylation of β-trichloro(trifluoro)methyl aryl enones with indoles
Wang, Wentao,Lian, Xiangjin,Chen, Donghui,Liu, Xiaohua,Lin, Lili,Feng, Xiaoming
supporting information; experimental part, p. 7821 - 7823 (2011/09/12)
An efficient yttrium(iii)-catalyzed highly enantioselective Friedel-Crafts alkylation of β-trichloro(trifluoro)methyl aryl enones is described. The reaction delivered a series of functionalized indoles with a chiral tertiary carbon center bearing a trichloro(trifluoro)methyl group in excellent results (up to 96% ee and 99% yield) under mild conditions.
