1316250-64-2Relevant academic research and scientific papers
Organometallic pyridylnaphthalimide complexes as protein kinase inhibitors
Blanck, Sebastian,Cruchter, Thomas,Vultur, Adina,Riedel, Radostan,Harms, Klaus,Herlyn, Meenhard,Meggers, Eric
, p. 4598 - 4606 (2011/11/28)
A new metal-containing scaffold for the design of protein kinase inhibitors is introduced. The key feature is a 3-(2-pyridyl)-1,8-naphthalimide "pharmacophore chelate ligand", which is designed to form two hydrogen bonds with the hinge region of the ATP-b
