1316275-31-6

Basic information

• Product Name: 2-Bromoquinazoline
• Synonyms: 2-Bromoquinazoline;2-Bromoquizoline
• CAS NO: 1316275-31-6
• Molecular Formula: C₈H₅BrN₂
• Molecular Weight: 209.0427
• Mol File: 1316275-31-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 351.5±25.0 °C(Predicted)
• Appearance: /
• Density: 1.656±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 0.17±0.30(Predicted)
• CAS DataBase Reference: 2-Bromoquinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromoquinazoline(1316275-31-6)
• EPA Substance Registry System: 2-Bromoquinazoline(1316275-31-6)

Safety Data

• Hazardous Substances Data: 1316275-31-6(Hazardous Substances Data)

Usage

Uses

2-Bromoquinazoline is a useful reagent in the preparation of triphenylene-?based polycyclic aromatic hydrocarbons (PAHs) from ring-?fused benzocyclobutenols (RBCBs) via the cleavage of the C-?C σ-?bond.

Upstream product

• 54145-20-9 quinazoline 1-oxide 

Relevant articles and documents

A highly practical and convenient halogenation of fused heterocyclic N-oxides

A novel, simple and practical method for the regioselective halogenation of fused heterocyclic N-oxides has been developed. It employs Vilsmeier reagent, generated in situ by POX3and DMF, as both the activating agent and the nucleophilic halide source. The method is amenable across a broad range of substrates, including quinolines, isoquinolines and the diazine N-oxides, possessing a variety of substitution patterns. Furthermore, all of the reagents associated are cheap and easy to obtain. The potential extension of this method to a one-pot oxidation/halogenation sequence that obviates the need for isolation of the N-oxide intermediates is also presented.