131633-01-7

Upstream product

• 105-39-5 chloroacetic acid ethyl ester 
• 131583-56-7 1-[1-(4-Hydroxy-benzoyl)-piperidin-4-yl]-3,4-dihydro-1H-quinolin-2-one 

Downstream Products

• 155436-90-1 2-Acetylamino-2-(2-{4-[4-(2-oxo-3,4-dihydro-2H-quinolin-1-yl)-piperidine-1-carbonyl]-phenoxy}-ethyl)-malonic acid diethyl ester 
• 159397-68-9 2-Acetylamino-2-(2-{4-[4-(2-oxo-3,4-dihydro-2H-quinolin-1-yl)-piperidine-1-carbonyl]-phenoxy}-ethyl)-malonic acid monoethyl ester 
• 186908-13-4 2-Acetylamino-4-{4-[4-(2-oxo-3,4-dihydro-2H-quinolin-1-yl)-piperidine-1-carbonyl]-phenoxy}-butyric acid ethyl ester 
• 186908-18-9 2-Acetylamino-4-{4-[4-(2-oxo-3,4-dihydro-2H-quinolin-1-yl)-piperidine-1-carbonyl]-phenoxy}-butyric acid 
• 186908-04-3 Methanesulfonic acid 2-{4-[4-(2-oxo-3,4-dihydro-2H-quinolin-1-yl)-piperidine-1-carbonyl]-phenoxy}-ethyl ester 
• 155436-88-7 1-{1-[4-(2-Iodo-ethoxy)-benzoyl]-piperidin-4-yl}-3,4-dihydro-1H-quinolin-2-one 
• 155436-86-5 1-{1-[4-(2-Hydroxy-ethoxy)-benzoyl]-piperidin-4-yl}-3,4-dihydro-1H-quinolin-2-one 

Relevant academic research and scientific papers

Synthesis and pharmacological activity of metabolites of vasopressin V1 receptor antagonist, OPC-21268

The metabolites of 1-[1-[4-(3-acetylaminopropoxy)benzoyl]-4- piperid-yl]-3,4-dihydro-2(1H)-quinolinone (OPC-21268, 1), vasopressin V1 receptor antagonist were synthesized to confirm the proposed structures and to examine their vasopressin Vsub