131633-06-2Relevant academic research and scientific papers
Orally active, nonpeptide vasopressin V1 antagonists. A novel series of 1-(1-substituted 4-piperidyl)-3,4-dihydro-2(1H)-quinolinone
Ogawa,Yamamura,Miyamoto,Kondo,Yamashita,Nakaya,Chihara,Mori,Tominaga,Yabuuchi
, p. 2011 - 2017 (2007/10/02)
A series of compounds has been synthesized and demonstrated to be antagonists of V1 receptors both in vitro and in vivo. These compounds are structurally related to the 1-(4-piperidyl)-2(1H)-quinolinones, including OPC-21268, an orally bioavail
