131671-04-0

Basic information

• Product Name: N-ethoxalyl-5-methoxy-2-nitroaniline
• CAS NO: 131671-04-0
• Molecular Weight: 268.226
• Mol File: 131671-04-0.mol

Chemical Properties

• CAS DataBase Reference: N-ethoxalyl-5-methoxy-2-nitroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-ethoxalyl-5-methoxy-2-nitroaniline(131671-04-0)
• EPA Substance Registry System: N-ethoxalyl-5-methoxy-2-nitroaniline(131671-04-0)

Safety Data

• Hazardous Substances Data: 131671-04-0(Hazardous Substances Data)

Upstream product

• 16133-49-6 5-methoxy-2-nitroaniline 
• 4755-77-5 Ethyl oxalyl chloride 

Downstream Products

• 420136-91-0 (4-benzylpiperidin-1-yl)-(6-hydroxy-1H-benzimidazol-2-yl)-methanone 
• 420137-33-3 6-hydroxy-1H-benzimidazole-2-carboxylic acid 

Relevant articles and documents

Benzimidazole-2-carboxamides as novel NR2B selective NMDA receptor antagonists

A novel series of benzimidazole-2-carboxamide derivatives was prepared and identified as NR2B selective NMDA receptor antagonists. The influence of some structural elements, like H-bond donor groups placed on the benzimidazole skeleton and the substitution pattern of the piperidine ring, on the biological activity was studied. Compound 6a showed excellent analgetic activity in the mouse formalin test following po administration.

2,3-quinoxalinediones for use as neuroleptics

Heterocyclic dihydroxyquinoxaline compounds having the formula STR1 wherein R 1 is hydroxy, alkoxy, aryloxy, aralkyloxy, cycloalkylalkoxy, cycloalkoxy, or acyloxy; andR 5, R 6, R 7 and R 8 independently are hydrogen, NO 2, halogen CN, SO 2 NR''R'', SO 2 R'', CF 3, or OR'', wherein R'' is hydrogen or C 1-4 -alkyl;The invention also relates to a method of preparing the compounds, pharmaceutical compositions thereof, and their use.The compounds are useful in the treatment of indications caused by hyperactivity of the excitatory neurotransmitters, particularly the quisqualate receptors, and especially as neuroleptics.