1316754-00-3Relevant academic research and scientific papers
A series of naphthalimide azoles: Design, synthesis and bioactive evaluation as potential antimicrobial agents
Damu, Guri L. V.,Wang, Qingpeng,Zhang, Huizhen,Zhang, Yiyi,Lv, Jingsong,Zhou, Chenghe
, p. 952 - 969 (2013/08/23)
A series of naphthalimide azoles as potential antibacterial and antifungal agents were conveniently and efficiently synthesized starting from commercially available 6-bromobenzo[de]isochromene-1,3-dione. All the new compounds were characterized by NMR, IR
Synthesis and activities of naphthalimide azoles as a new type of antibacterial and antifungal agents
Zhang, Yi-Yi,Zhou, Cheng-He
, p. 4349 - 4352 (2011/08/10)
Naphthalimide-derived azoles as a new type of antimicrobial agents were synthesized and evaluated for their efficiency in vitro against eight bacteria and two fungi by two fold serial dilution technique. Most title compounds exhibited good antimicrobial p
Synthesis of novel fluconazoliums and their evaluation for antibacterial and antifungal activities
Zhang, Yi-Yi,Mi, Jia-Li,Zhou, Cheng-He,Zhou, Xiang-Dong
, p. 4391 - 4402 (2011/11/06)
A series of novel fluconazoliums were synthesized and their bioactive evaluation as potential antibacterial and antifungal agents were described. Some target compounds displayed good and broad-spectrum antimicrobial activities with low MIC values ranging from 0.25 to 64 μg/mL against all the tested strains, including three Gram-positive bacteria (Staphylococcus aureus, MRSA and Bacillus subtilis), three Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa and Bacillus proteus) as well as two fungi (Candida albicans and Aspergillus fumigatus). Among all tested title compounds, the octyl, dichlorobenzyl, naphthyl and naphthalimino derivatives gave comparable or even better antibacterial and antifungal efficiency in comparison with the reference drugs Fluconazole, Chloromycin and Norfloxacin.
