13170-28-0

Upstream product

• 619-50-1 4-nitrobenzoic acid methyl ester 
• 619-45-4 4-methoxycarbonyl aniline 
• 99768-12-4 4-methoxycarbonylphenylboronic acid 
• 24226-29-7 N-[(4-methoxycarbonyl)phenyl]hydroxylamine 

Downstream Products

• 51751-68-9 4-(3-oxo-4,4-diphenyl-[1,2]oxazetidin-2-yl)-benzoic acid methyl ester 
• 90030-17-4 2-(p-carbomethoxyphenyl)-4-methoxy-3,6-dihydro-2H-1,2-oxazine 
• 119435-72-2 4-(4-Isopropyl-phenylazo)-benzoic acid 
• 23663-92-5 dimethyl 4,4'-azoxydibenzoate 
• 127717-72-0 methyl 9-hydroxy-3-methyl-9H-pyrrolo<1,2-a>indol-7-carboxylate 
• 421547-21-9 C₁₅H₁₃NO₃ 
• 82698-71-3 4-(3,6-Dihydro-[1,2]oxazin-2-yl)-benzoic acid methyl ester 
• 37790-20-8 (E)-4-(phenyldiazenyl)benzoic acid 
• 181767-88-4 4-(2-oxa-3-azabicyclo[2.2.2]oct-5-en-3-yl)benzoic acid methyl ester 
• 219141-82-9 K⁽¹⁺⁾*PtCl₃(NOC₆H₄CO₂CH₃)^(1-)=K[PtCl₃(NOC₆H₄CO₂CH₃)] 

Relevant academic research and scientific papers

Efficient preparation of nitrosoarenes for the synthesis of azobenzenes

(Chemical Equation Presented) Reaction conditions are described for the oxidation of anilines furnishing nitrosoarenes and the synthesis of unsymmetrically substituted azobenzenes. In a comparative study, the catalytic oxidation of methyl 4-aminobenzoate

Catalytic Oxidation of Primary Aromatic Amines to the Corresponding Nitroso Compounds by H2O2 and (hmpa = Hexamethylphosphoric Triamide)

1 catalyses the oxidation of primary aromatic amines to the corresponding nitroso derivatives, in the presence of H2O2 as oxidant.

Continuous Flow Synthesis of Azoxybenzenes by Reductive Dimerization of Nitrosobenzenes with Gel-Bound Catalysts

In the search for a new synthetic pathway for azoxybenzenes with different substitution patterns, an approach using a microfluidic reactor with gel-bound proline organocatalysts under continuous flow is presented. Herein the formation of differently substituted azoxybezenes by reductive dimerization of nitrosobenzenes within minutes at mild conditions in good to almost quantitative yields is described. The conversion within the microfluidic reactor is analyzed and used for optimizing and validating different parameters. The effects of the different functionalities on conversion, yield, and reaction times are analyzed in detail by NMR. The applicability of this reductive dimerization is demonstrated for a wide range of differently substituted nitrosobenzenes. The effects of these different functionalities on the structure of the obtained azoxyarenes are analyzed in detail by NMR and single-crystal X-ray diffraction. Based on these results, the turnover number and the turnover frequency were determined.

Phenylimino Indolinone: A Green-Light-Responsive T-Type Photoswitch Exhibiting Negative Photochromism

Imines are photoaddressable motifs useful in the development of new generations of molecular switches, but their operation with low-energy photons and control over isomer stability remain challenging. Based on a computational design, we developed phenylimino indolinone (PIO), a green-light-addressable T-type photoswitch showing negative photochromism. The isomerization behavior of this photoactuator of the iminothioindoxyl (ITI) class was studied using time-resolved spectroscopies on time scales from femtoseconds to the steady state and by quantum-chemical analyses. The understanding of the isomerization properties and substituent effects governing these photoswitches opens new avenues for the development of novel T-type visible-light-addressable photoactuators based on C=N bonds.

PHOTORESPONSIVE COMPOUND

PROBLEM TO BE SOLVED: To provide a novel photoresponsive compound that is useful as a medicament, or a reagent for analyzing in vivo intermolecular interaction, or the like. SOLUTION: Provided is a compound represented by the following formula (I-1) or (I

PHOTOCONTROLLED DYNAMIC COVALENT LINKERS FOR POLYMER NETWORKS

Reversibly crosslinkable polymeric networks, including reversibly crosslinkable hydrogel networks are provided. Also provided are methods of making the polymeric networks and methods of using the hydrogel networks in tissue engineering applications. The r

Enantioselective Oxidative Coupling of β-Ketocarbonyls and Anilines by Joint Chiral Primary Amine and Selenium Catalysis

An enantioselective primary amine-catalyzed total N-selective nitroso aldol reaction (N-NA) was achieved through the oxidation of primary aromatic amines to the corresponding nitrosoarenes catalyzed by selenium reagents and 30% H2O2. This protocol provides a facile and highly efficient access to α-hydroxyamino carbonyls bearing chiral quaternary centers under exceedingly mild and green reaction conditions with high chemo-and enantiocontrol.

Structure-switching M3L2 Ir(iii) coordination cages with photo-isomerising azo-aromatic linkers

Cyclotriguaiacylene has been functionalised with 3- or 4-pyridyl-azo-phenyl groups to form a series of molecular hosts with three azobenzene-type groups that exhibit reversible photo-isomerisation. Reaction of the host molecules with [Ir(C^N)2(

Rh(III)-Catalyzed bilateral cyclization of aldehydes with nitrosos toward unsymmetrical acridines proceeding with C-H functionalization enabled by a transient directing group

A Rh(iii)-catalyzed bilateral cyclization was developed for the efficient construction of acridines proceeding with C-H functionalization whereby in situ formation and removal of an imino transient directing group in the presence of catalytic amount of BnNH2 are achieved. In this transformation, a sequential Rh(iii)-catalyzed C-H amination, cyclization, and aromatization process was involved.

Access to Fully Substituted Thiazoles and 2,3-Dihydrothiazoles via Copper-Catalyzed [4 + 1] Heterocyclization of α-(N-Hydroxy/aryl)imino-β-oxodithioesters with α-Diazocarbonyls

An efficient chemoselective practical route to fully substituted thiazoles and 2,3-dihydrothiazoles has been devised by [4 + 1] heterocyclization of α-(N-hydroxy/aryl)imino-β-oxodithioesters with in situ generated Cu-carbenoids of diazocarbonyls. The α-(N-hydroxy/aryl)imino-β-oxodithioesters are readily accessible by the reaction of β-oxodithioesters with nitrous acid/nitrosoarenes. The overall transformation involves sequential N-O/C-N bonds cleavage followed by cascade C-N/C-S bonds formation in one-pot. This new strategy allows full control over the introduction of various sensitive functional groups at different positions of the thiazole ring, broadening the arsenal of synthetic methods to obtain such scaffolds.