Welcome to LookChem.com Sign In|Join Free

CAS

  • or

13171-00-1

Post Buying Request

13171-00-1 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

13171-00-1 Usage

Identification

▼▲ CAS.No.:? 13171-00-1? FL.No.:? 7.133 FEMA.No.:? 3653 NAS.No.:? 3653 CoE.No.:? n/a? EINECS.No.:? 236-114-4? JECFA.No.:? 812

Description

A crystalline compound with a musky, sweet, animal odor.

Regulatory Status

CoE: n/a FDA: n/a FDA (other): n/a JECFA: Additional data required (2001).

Natural occurrence

Reported found in cooked asparagus.

Chemical Properties

Different sources of media describe the Chemical Properties of 13171-00-1 differently. You can refer to the following data:
1. White Solid
2. Celestolide is a musk fragrance that is prepared by reacting tert-butylbenzene with isoprene in the presence of sulfuric acid, followed by acetylation of the resulting 1 (cipher),1-dimethyl-6-tertbutylindane: The indane is light-stable and is mainly used for perfuming soap and cosmetics.
3. A crystalline compound with a musky, sweet, animal odor

Occurrence

Reported found in cooked asparagus

Uses

Used for fragrance compositions and perfumes with long-lasting fragrance

Preparation

From tert-butylbenzene

Taste threshold values

Taste characteristics at 20 ppm: solvent-like with a dirty, musty brown, earthy nuance.

Flammability and Explosibility

Notclassified

Trade name

Celestolide (IFF).

Check Digit Verification of cas no

The CAS Registry Mumber 13171-00-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,1,7 and 1 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 13171-00:
(7*1)+(6*3)+(5*1)+(4*7)+(3*1)+(2*0)+(1*0)=61
61 % 10 = 1
So 13171-00-1 is a valid CAS Registry Number.
InChI:InChI=1/C17H24O/c1-5-6-7-13-10-15(12(2)18)14-8-9-17(3,4)16(14)11-13/h10-11H,5-9H2,1-4H3

13171-00-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(6-(tert-Butyl)-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl)ethanone

1.2 Other means of identification

Product number -
Other names 1-(6-tert-butyl-1,1-dimethyl-2,3-dihydroinden-4-yl)ethanone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13171-00-1 SDS

13171-00-1Synthetic route

6-tert-butyl-1,1-dimethylindane
3605-31-0

6-tert-butyl-1,1-dimethylindane

acetyl chloride
75-36-5

acetyl chloride

Celestolide
13171-00-1

Celestolide

Conditions
ConditionsYield
With aluminium trichloride In dichloromethane Friedel-Crafts reaction;62%
With tetrachloromethane; aluminium trichloride
aluminium trichloride In hexane
6-tert-butyl-1,1-dimethylindane
3605-31-0

6-tert-butyl-1,1-dimethylindane

acetyl chloride
75-36-5

acetyl chloride

A

6-acetyl-1,1-dimethyl-4-tertbutylindane
102296-26-4

6-acetyl-1,1-dimethyl-4-tertbutylindane

B

Celestolide
13171-00-1

Celestolide

C

1-(3,3-dimethylindan-5-yl)ethanone
102296-45-7

1-(3,3-dimethylindan-5-yl)ethanone

D

1-(1,1-dimethyl-2,3-dihydro-1H-inden-5-yl)ethan-1-one
102296-44-6

1-(1,1-dimethyl-2,3-dihydro-1H-inden-5-yl)ethan-1-one

Conditions
ConditionsYield
With aluminium trichloride In various solvent(s) at 0 - 5℃; for 1h; Further byproducts given;A n/a
B 50.4%
C n/a
D n/a
With aluminium trichloride In various solvent(s) at 0 - 5℃; for 1h; Further byproducts given;
6-tert-butyl-1,1-dimethylindane
3605-31-0

6-tert-butyl-1,1-dimethylindane

acetyl chloride
75-36-5

acetyl chloride

A

Celestolide
13171-00-1

Celestolide

B

1-(3,3-dimethylindan-5-yl)ethanone
102296-45-7

1-(3,3-dimethylindan-5-yl)ethanone

Conditions
ConditionsYield
With tetrachloromethane; aluminium trichloride
5-(tert-butyl)-1,1-dimethyl-2,3-dihydro-1H-indene
38393-97-4

5-(tert-butyl)-1,1-dimethyl-2,3-dihydro-1H-indene

acetyl chloride
75-36-5

acetyl chloride

Celestolide
13171-00-1

Celestolide

Conditions
ConditionsYield
With aluminium trichloride; nitrobenzene; 1,2-dichloro-ethane
6-tert-butyl-1,1-dimethylindane
3605-31-0

6-tert-butyl-1,1-dimethylindane

acetyl chloride
75-36-5

acetyl chloride

A

6-acetyl-1,1-dimethyl-4-tertbutylindane
102296-26-4

6-acetyl-1,1-dimethyl-4-tertbutylindane

B

Celestolide
13171-00-1

Celestolide

C

1-(3,3-dimethylindan-5-yl)ethanone
102296-45-7

1-(3,3-dimethylindan-5-yl)ethanone

D

5-acetyl-1,1-dimethyl-6-tert-butylindane
133631-95-5

5-acetyl-1,1-dimethyl-6-tert-butylindane

Conditions
ConditionsYield
With aluminium trichloride In various solvent(s) at 0 - 5℃; for 1h; Further byproducts given. Title compound not separated from byproducts;
6-tert-butyl-1,1-dimethylindane
3605-31-0

6-tert-butyl-1,1-dimethylindane

acetyl chloride
75-36-5

acetyl chloride

A

6-acetyl-1,1-dimethyl-4-tertbutylindane
102296-26-4

6-acetyl-1,1-dimethyl-4-tertbutylindane

B

Celestolide
13171-00-1

Celestolide

C

1-(1,1-dimethyl-2,3-dihydro-1H-inden-5-yl)ethan-1-one
102296-44-6

1-(1,1-dimethyl-2,3-dihydro-1H-inden-5-yl)ethan-1-one

D

6-acetyl-1,1-dimethyl-5-tert-butylindane
132684-99-2

6-acetyl-1,1-dimethyl-5-tert-butylindane

Conditions
ConditionsYield
With aluminium trichloride In various solvent(s) at 0 - 5℃; for 1h; Further byproducts given. Title compound not separated from byproducts;
aluminium trichloride
7446-70-0

aluminium trichloride

6-tert-butyl-1,1-dimethylindane
3605-31-0

6-tert-butyl-1,1-dimethylindane

nitrobenzene
98-95-3

nitrobenzene

1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

acetyl chloride
75-36-5

acetyl chloride

Celestolide
13171-00-1

Celestolide

aluminium trichloride
7446-70-0

aluminium trichloride

6-tert-butyl-1,1-dimethylindane
3605-31-0

6-tert-butyl-1,1-dimethylindane

acetyl chloride
75-36-5

acetyl chloride

CCl2

CCl2

Celestolide
13171-00-1

Celestolide

tert-butylbenzene
253185-03-4, 253185-04-5

tert-butylbenzene

Celestolide
13171-00-1

Celestolide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 50 percent / AlCl3 / nitromethane
2: 62 percent / AlCl3 / CH2Cl2
View Scheme
isoprene
78-79-5

isoprene

Celestolide
13171-00-1

Celestolide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 50 percent / AlCl3 / nitromethane
2: 62 percent / AlCl3 / CH2Cl2
View Scheme
6-tert-butyl-1,1-dimethyl-4-indancarboxylic acid
61813-34-1

6-tert-butyl-1,1-dimethyl-4-indancarboxylic acid

Celestolide
13171-00-1

Celestolide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: quinoline; CuO; copper-powder / 200 - 230 °C
2: AlCl3; CCl4
View Scheme
1,1-dimethylindan
4912-92-9

1,1-dimethylindan

Celestolide
13171-00-1

Celestolide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: AlCl3; CS2
2: AlCl3; CCl4
View Scheme
Multi-step reaction with 2 steps
1: AlCl3; CS2
2: AlCl3; 1,2-dichloro-ethane; nitrobenzene
View Scheme
Multi-step reaction with 2 steps
1: concentrated H2SO4
2: AlCl3; CCl4
View Scheme
Multi-step reaction with 2 steps
1: concentrated H2SO4
2: AlCl3; CCl4
View Scheme
4-Phenyl-2-butanone
2550-26-7

4-Phenyl-2-butanone

Celestolide
13171-00-1

Celestolide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: H2SO4
2: methyl magnesium bromide; diethyl ether
3: aqueous H2SO4
4: AlCl3; CCl4
View Scheme
4-(4-tert-butylphenyl)butan-2-one
65170-86-7

4-(4-tert-butylphenyl)butan-2-one

Celestolide
13171-00-1

Celestolide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: methyl magnesium bromide; diethyl ether
2: aqueous H2SO4
3: AlCl3; CCl4
View Scheme
4-(4-tert-butyl-phenyl)-2-methyl-butan-2-ol
72390-27-3

4-(4-tert-butyl-phenyl)-2-methyl-butan-2-ol

Celestolide
13171-00-1

Celestolide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aqueous H2SO4
2: AlCl3; CCl4
View Scheme
Multi-step reaction with 2 steps
1: aqueous H2SO4
2: AlCl3; CCl4
View Scheme
6-tert-butyl-3,3-dimethyl-1-indanone
38393-94-1

6-tert-butyl-3,3-dimethyl-1-indanone

Celestolide
13171-00-1

Celestolide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: N2H4+H2O; KOH; triethylene glycol / 210 °C
2: AlCl3; 1,2-dichloro-ethane; nitrobenzene
View Scheme
3-(4-tert-butyl-phenyl)propionic acid methyl ester
1211-99-0

3-(4-tert-butyl-phenyl)propionic acid methyl ester

Celestolide
13171-00-1

Celestolide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: methyl magnesium bromide; diethyl ether
2: aqueous H2SO4
3: AlCl3; CCl4
View Scheme
Multi-step reaction with 3 steps
1: methyl magnesium bromide; diethyl ether
2: aqueous H2SO4
3: AlCl3; CCl4
View Scheme
Celestolide
13171-00-1

Celestolide

1-(6-tert-butyl-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl)ethanol

1-(6-tert-butyl-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl)ethanol

Conditions
ConditionsYield
With methanol; sodium tetrahydroborate at 0℃; for 4.33333h; Time;98.2%
Celestolide
13171-00-1

Celestolide

6-tert-butyl-1,1-dimethyl-2,3-dihydro-1H-inden-4-amine
132567-92-1

6-tert-butyl-1,1-dimethyl-2,3-dihydro-1H-inden-4-amine

Conditions
ConditionsYield
With methanol; O-benzenesulfonyl-acetohydroxamic acid ethyl ester; toluene-4-sulfonic acid at 23℃; for 24h; Inert atmosphere;95%
Multi-step reaction with 3 steps
1: NH2OH*HCl; pyridine / ethanol
2: SOCl2 / CH2Cl2
3: aq. HCl / ethanol / Heating
View Scheme
Celestolide
13171-00-1

Celestolide

1-(3-azido-6-(tert-butyl)-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl)ethan-1-one

1-(3-azido-6-(tert-butyl)-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl)ethan-1-one

Conditions
ConditionsYield
With trimethylsilylazide; copper diacetate; (S,S)-4,4'-bis(phenylmethyl)-2,2',5,5'-tetrahydro-2,2'-bioxazole; N-fluorobis(benzenesulfon)imide In nitromethane at 30℃; for 24h; Inert atmosphere; Sealed tube;92%
With sodium azide; iodosylbenzene; C32H46ClMnN2O2 In water; ethyl acetate at 23℃;74%
With sodium azide; lithium perchlorate In acetic acid; acetonitrile at 25℃; for 10h; Inert atmosphere; Electrochemical reaction;65%
With sodium azide; 1,10-Phenanthroline; manganese(II) fluoride; lithium perchlorate; trifluoroacetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone In acetic acid; 1,2-dichloro-ethane; acetonitrile at 35℃; for 21h; Inert atmosphere; Electrolysis; Irradiation; Schlenk technique;51%
Celestolide
13171-00-1

Celestolide

1-(6-(tert-butyl)-3-chloro-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl)ethan-1-one

1-(6-(tert-butyl)-3-chloro-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl)ethan-1-one

Conditions
ConditionsYield
With dichloro(1,10-phenanthroline) copper(II); 1-azido-1λ3-benzo[d][1,2]iodaoxol-3(1H)-one In acetonitrile at 20℃; for 48h; Reagent/catalyst; Solvent; Inert atmosphere; Sealed tube;91%
Celestolide
13171-00-1

Celestolide

1-(6-(tert-butyl)-3-fluoro-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl)ethan-1-one

1-(6-(tert-butyl)-3-fluoro-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl)ethan-1-one

Conditions
ConditionsYield
With xanth-9-one; Selectfluor In acetonitrile at 60℃; for 0.15h; Inert atmosphere; Flow reactor; Irradiation;88%
With (S,S)-chloro[2,2'-[1,2-cyclohexanediylbis(nitrilomethylidyne)]bis-[4,6-bis(1,1-dimethylethyl)phenolato]](2-)-N,N',O,O'-manganese; iodosylbenzene; triethylamine tris(hydrogen fluoride) In acetonitrile at 50℃; Reagent/catalyst; Temperature; Time; Schlenk technique; Inert atmosphere;67%
With (S,S)-chloro[2,2'-[1,2-cyclohexanediylbis(nitrilomethylidyne)]bis-[4,6-bis(1,1-dimethylethyl)phenolato]](2-)-N,N',O,O'-manganese; iodosylbenzene; triethylamine tris(hydrogen fluoride) In acetonitrile at 50℃; Schlenk technique; Inert atmosphere;
With dihydroxy-methyl-borane; bathophenanthroline; copper (I) acetate; lithium carbonate; N-fluorobis(benzenesulfon)imide In chlorobenzene at 45℃; for 16h; Glovebox; Inert atmosphere;
Celestolide
13171-00-1

Celestolide

N-(6-tert-butyl-1,1-dimethylindan-4-yl)acetamide
101866-05-1

N-(6-tert-butyl-1,1-dimethylindan-4-yl)acetamide

Conditions
ConditionsYield
With O-benzenesulfonyl-acetohydroxamic acid ethyl ester; toluene-4-sulfonic acid In water; acetonitrile at 23℃; for 24h; Inert atmosphere;87%
Multi-step reaction with 2 steps
1: NH2OH*HCl; pyridine / ethanol
2: SOCl2 / CH2Cl2
View Scheme
2-(aminoxy)acetic acid hydrochloride

2-(aminoxy)acetic acid hydrochloride

Celestolide
13171-00-1

Celestolide

C19H27NO3

C19H27NO3

Conditions
ConditionsYield
With sodium acetate In methanol at 20℃;85.9%
Celestolide
13171-00-1

Celestolide

7-acetyl-5-tert-butyl-3,3-dimethyl-indan-1-one

7-acetyl-5-tert-butyl-3,3-dimethyl-indan-1-one

Conditions
ConditionsYield
With tert.-butylhydroperoxide In water; acetonitrile at 50℃; for 15h; Electrolysis;74%
With tetra-O-acetyl riboflavin; ferrous perchlorate; oxygen In water; acetonitrile at 50℃; for 0.416667h; UV-irradiation; Flow reactor;7%
Celestolide
13171-00-1

Celestolide

t-butyldimethylsiyl triflate
69739-34-0

t-butyldimethylsiyl triflate

tert-butyl((1-(6-(tert-butyl)-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl)vinyl)oxy)dimethylsilane

tert-butyl((1-(6-(tert-butyl)-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl)vinyl)oxy)dimethylsilane

Conditions
ConditionsYield
Stage #1: Celestolide With triethylamine In dichloromethane at 20℃; for 1h; Schlenk technique; Inert atmosphere;
Stage #2: t-butyldimethylsiyl triflate In dichloromethane for 3h; Schlenk technique; Inert atmosphere;
70%
2-((trifluoromethyl)thio)isoindoline-1,3-dione
719-98-2

2-((trifluoromethyl)thio)isoindoline-1,3-dione

Celestolide
13171-00-1

Celestolide

C18H23F3OS

C18H23F3OS

Conditions
ConditionsYield
With (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; potassium carbonate In acetonitrile at 20℃; for 12h; Inert atmosphere; Irradiation;62%
Celestolide
13171-00-1

Celestolide

(2,2’-bipyridine)Zn(CF3)2

(2,2’-bipyridine)Zn(CF3)2

1-(6-(tert-butyl)-1,1-dimethyl-3-(trifluoromethyl)-2,3-dihydro-1H-inden-4-yl)ethanone

1-(6-(tert-butyl)-1,1-dimethyl-3-(trifluoromethyl)-2,3-dihydro-1H-inden-4-yl)ethanone

Conditions
ConditionsYield
With zinc diacetate; copper(l) cyanide; zinc trifluoromethanesulfonate; N-fluorobis(benzenesulfon)imide at 20℃; for 24h; Sealed tube; Inert atmosphere;53%
[bis(acetoxy)iodo]benzene
3240-34-4

[bis(acetoxy)iodo]benzene

Celestolide
13171-00-1

Celestolide

7-acetyl-5-(tert-butyl)-3,3-dimethyl-2,3-dihydro-1H-inden-1-yl acetate

7-acetyl-5-(tert-butyl)-3,3-dimethyl-2,3-dihydro-1H-inden-1-yl acetate

Conditions
ConditionsYield
With 9-mesityl-1,3,6,8-tetramethoxy-10-phenylacridin-10-ium tetrafluoroborate In dichloromethane at 25 - 40℃; for 24h; Schlenk technique; Inert atmosphere; Irradiation;41%
Celestolide
13171-00-1

Celestolide

6-tert-butyl-1,1-dimethyl-4-indancarboxylic acid
61813-34-1

6-tert-butyl-1,1-dimethyl-4-indancarboxylic acid

Conditions
ConditionsYield
With sodium hypochlorite; sodium hypobromide
With 1,4-dioxane; potassium hypobromite
With sodium hypobromide In 1,4-dioxane
Celestolide
13171-00-1

Celestolide

4-ethyl-6-tert-butyl-1,1-dimethyl-indan
3247-65-2

4-ethyl-6-tert-butyl-1,1-dimethyl-indan

Conditions
ConditionsYield
With methanol; platinum on activated charcoal; palladium dichloride Hydrogenation;
Celestolide
13171-00-1

Celestolide

diethyl chlorophosphate
814-49-3

diethyl chlorophosphate

phosphoric acid 1-(6-tert-butyl-1,1-dimethyl-indan-4-yl)-vinyl ester diethyl ester

phosphoric acid 1-(6-tert-butyl-1,1-dimethyl-indan-4-yl)-vinyl ester diethyl ester

Conditions
ConditionsYield
Stage #1: Celestolide With lithium diisopropyl amide In tetrahydrofuran at -78℃;
Stage #2: diethyl chlorophosphate In tetrahydrofuran
Stage #1: Celestolide With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere;
Stage #2: diethyl chlorophosphate In tetrahydrofuran at -78 - 20℃; for 1h; Inert atmosphere;
Celestolide
13171-00-1

Celestolide

1-(6-tert-butyl-1,1-dimethyl-indan-4-yl)-ethanone oxime
175136-27-3

1-(6-tert-butyl-1,1-dimethyl-indan-4-yl)-ethanone oxime

Conditions
ConditionsYield
With pyridine; hydroxylamine hydrochloride In ethanol
With hydroxylamine hydrochloride; sodium acetate In ethanol at 90℃; for 2h; Sealed tube; Inert atmosphere;
Celestolide
13171-00-1

Celestolide

(2E,4E)-6-(6-tert-Butyl-1,1-dimethyl-indan-4-ylamino)-3-methyl-hexa-2,4-dienoic acid ethyl ester
889444-00-2

(2E,4E)-6-(6-tert-Butyl-1,1-dimethyl-indan-4-ylamino)-3-methyl-hexa-2,4-dienoic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: NH2OH*HCl; pyridine / ethanol
2: SOCl2 / CH2Cl2
3: aq. HCl / ethanol / Heating
4: NaCNBH3; ZnCl2 / methanol
View Scheme
Celestolide
13171-00-1

Celestolide

(2E,4E)-6-[(6-tert-Butyl-1,1-dimethyl-indan-4-yl)-isopropyl-amino]-3-methyl-hexa-2,4-dienoic acid ethyl ester
886861-94-5

(2E,4E)-6-[(6-tert-Butyl-1,1-dimethyl-indan-4-yl)-isopropyl-amino]-3-methyl-hexa-2,4-dienoic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: NH2OH*HCl; pyridine / ethanol
2: SOCl2 / CH2Cl2
3: aq. HCl / ethanol / Heating
4: NaCNBH3; ZnCl2 / methanol
5: K2CO3 / N,N-dimethyl-acetamide
View Scheme
Celestolide
13171-00-1

Celestolide

(2E,4E)-6-[(6-tert-Butyl-1,1-dimethyl-indan-4-yl)-isopropyl-amino]-3-methyl-hexa-2,4-dienoic acid

(2E,4E)-6-[(6-tert-Butyl-1,1-dimethyl-indan-4-yl)-isopropyl-amino]-3-methyl-hexa-2,4-dienoic acid

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: NH2OH*HCl; pyridine / ethanol
2: SOCl2 / CH2Cl2
3: aq. HCl / ethanol / Heating
4: NaCNBH3; ZnCl2 / methanol
5: K2CO3 / N,N-dimethyl-acetamide
6: KOH / methanol
View Scheme
Celestolide
13171-00-1

Celestolide

(2E,4E)-6-[(6-tert-Butyl-1,1-dimethyl-indan-4-yl)-propyl-amino]-3-methyl-hexa-2,4-dienoic acid

(2E,4E)-6-[(6-tert-Butyl-1,1-dimethyl-indan-4-yl)-propyl-amino]-3-methyl-hexa-2,4-dienoic acid

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: NH2OH*HCl; pyridine / ethanol
2: SOCl2 / CH2Cl2
3: aq. HCl / ethanol / Heating
4: NaCNBH3; ZnCl2 / methanol
5: K2CO3 / N,N-dimethyl-acetamide
6: KOH / methanol
View Scheme

13171-00-1Relevant articles and documents

Aza-retinoids as novel retinoid X receptor-specific agonists

Farmer, Luc J.,Marron, Kristen S.,Canan Koch, Stacie S.,Hwang,Kallel, E. Adam,Zhi, Lin,Nadzan, Alex M.,Robertson, Dave W.,Bennani, Youssef L.

, p. 2352 - 2356 (2007/10/03)

A new structurally simple series of potent lipophilic aza-retinoids RXR agonists has been developed. SAR studies for the N-alkyl-azadienoic acids described here demonstrate that the RXR activity profile is sensitive to the N-alkyl chain length. Further, we have expanded the work to include azadienoic acids, which exhibited many accessible conformations leading to a better understanding of the SAR around the series.

STRUCTURE OF THE SIDE PRODUCTS IN THE SYNTHESIS OF 4-ACETYL-1,1-DIMETHYL-6-TERT-BUTYLINDANE

Smirnova, O. B.,Cherkaev, G. V.,Shekhtman, N. M.

, p. 2123 - 2127 (2007/10/02)

The minor products from the acetylation of 1,1-dimethyl-6-tert-butylindane with acetyl chloride were isolated and identified by PMR spectroscopy.The configuration of the substituents in isomeric compounds with an identical type of substitution in the aromatic ring was established by means of the long-range spin-spin coupling constants of the aromatic protons with the protons of the five-membered ring.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 13171-00-1