13174-96-4

Basic information

• Product Name: 1-(5-nitropyridin-2-yl)-1H-benzotriazole
• Synonyms: 1-(5-Nitro-2-pyridyl)-1H-benzotriazole
• CAS NO: 13174-96-4
• Molecular Formula: C₁₁H₇N₅O₂
• Molecular Weight: 241.2056
• Mol File: 13174-96-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 467.5°C at 760 mmHg
• Flash Point: 236.5°C
• Density: 1.56g/cm³
• Vapor Pressure: 6.5E-09mmHg at 25°C
• Refractive Index: 1.772
• CAS DataBase Reference: 1-(5-nitropyridin-2-yl)-1H-benzotriazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-nitropyridin-2-yl)-1H-benzotriazole(13174-96-4)
• EPA Substance Registry System: 1-(5-nitropyridin-2-yl)-1H-benzotriazole(13174-96-4)

Safety Data

• Hazardous Substances Data: 13174-96-4(Hazardous Substances Data)

Usage

General Description

1-(5-nitropyridin-2-yl)-1H-benzotriazole is a chemical compound with the molecular formula C11H7N5O2. It is a heterocyclic aromatic organic compound that contains a benzotriazole ring system with a 5-nitropyridine substituent. 1-(5-nitropyridin-2-yl)-1H-benzotriazole is commonly used as a corrosion inhibitor for metals and as a photostabilizer for plastics and coatings. It has also been studied as a potential pharmaceutical intermediate for the synthesis of biologically active compounds. The presence of the nitro group and the benzotriazole ring in its structure make it useful for applications related to the protection and stabilization of materials against environmental degradation and oxidation.

Upstream product

• 95-14-7 1,2,3-Benzotriazole 
• 456-24-6 2-Fluoro-5-nitropyridine 
• 4548-45-2 2-chloro-5-nitropyridine 

Relevant articles and documents

S(RN)1 based methodology for synthesis of 2-substituted nitropyridines

2-Chloronitropyridines react with the anion of benzyl cyanide, benzotriazole, imidazole, pyrrole and phthalimide to give the corresponding 2-substituted nitropyridines. The S(RN)1 mechanism was confirmed by EPR spectroscopy and depression of reaction rate

TRIFLUOROMETHOXYLATION OF ARENES VIA INTRAMOLECULAR TRIFLUOROMETHOXY GROUP MIGRATION

The present invention provides a process of producing a trifluoromethoxylated aryl or trifluoromethoxylated heteroaryl having the structure: (I), wherein A is an aryl or heteroaryl, each with or without subsutitution; and R1 is -H, -(alkyl), -(alkenyl), -(alkynyl), -(aryl), -(heteroaryl), - (alkylaryl), - (alkylheteroaryl), -NH-(alkyl), -N(alkyl)2, -NH-(alkenyl), -NH-(alkynyl) -NH-(aryl), -NH-(heteroaryl), -O-(alkyl), -O-(alkenyl), -O-(alkynyl), -O-(aryl), -O-(heteroaryl), -S-(alkyl), -S- (alkenyl), -S-(alkynyl), -S-(aryl), or -S-(heteroaryl), comprising: (a) reacting a compound having the structure: (II), with a trifluoromethylating agent in the presence of a base in a first suitable solvent under conditions to produce a compound having the structure: (III); and (b) maintaining the compound produced in step (a) in a second suitable solvent under conditions sufficient to produce the trifluoromethoxylated aryl or trifluormethoxylated heteroaryl having the structure: (I).