131741-53-2

Usage

Uses

Used in Pharmaceutical Industry:
1(2H)-Phthalazinone, 4-(4-aminophenyl)is used as a key intermediate in the synthesis of various pharmaceuticals and bioactive molecules. Its unique structure and reactivity allow for the development of new drugs with potential therapeutic applications.
Used in Organic Chemistry Research:
In the field of organic chemistry, 1(2H)-Phthalazinone, 4-(4-aminophenyl)is utilized for the development of new reactions and synthetic methodologies. Its versatile chemical properties enable researchers to explore novel approaches in chemical synthesis and compound design.
Used in Other Industrial Applications:
Due to its unique chemical properties and reactivity, 1(2H)-Phthalazinone, 4-(4-aminophenyl)may also have potential uses in other industrial applications. These could include the development of new materials, catalysts, or other specialized chemical products that can benefit from the compound's specific characteristics.

Upstream product

• 181660-06-0 2-(4-aminobenzoyl)-benzoic acid 

Relevant academic research and scientific papers

Synthesis of novel phthalazine derivatives as pharmacological activities

Phthalazine derivatives attached to amino acid derivatives were synthesized with high yields. The reaction of phthalazine derivatives with different phthalyl and tosylamino acids such as glycine, alanine, phenylalanine, valine, serine, and threonine in the presence of N,N-dicyclo hexylcarbodiimide (DCC) as a dehydrating agent reagent yielded high yields of the afforded compounds. Phthalylamino acids derivatives were obtained by deprotection of phthalazine derivatives, with the latter heating with hydrazine hydrate. The chemical structures of all phthalazine derivatives were affirmed by elemental analysis and spectral data (IR, MS, 1HNMR, and 13C NMR). Screening out and estimation of the synthesized derivatives for their cytotoxic and antioxidant activity were done, and most of them showed powerful activity in comparison with standard drugs.

Some pyrrole substituted aryl pyridazinone and phthalazinone derivatives and their antihypertensive activities

In this work, some 2-nonsubstituted/2-methyl-/2-(2-acetyloxyethyl)-6-[4- (substituted pyrrol-1-yl)phenyl]-4,5-dihydro-3(2H)-pyridazinone, derivatives and 2-nonsubstituted/2-methyl- 4-[4-(substituted pyrrol-1-yl)phenyl]-1(2H)- phthalazinone derivatives wer