131744-08-6

Basic information

• Product Name: 3-aminobutan-2-ol hydrochloride
• CAS NO: 131744-08-6
• Molecular Weight: 125.598
• Mol File: 131744-08-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-aminobutan-2-ol hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-aminobutan-2-ol hydrochloride(131744-08-6)
• EPA Substance Registry System: 3-aminobutan-2-ol hydrochloride(131744-08-6)

Safety Data

• Hazardous Substances Data: 131744-08-6(Hazardous Substances Data)

Upstream product

• 98946-17-9 2,2,2-trichloro-acetimidic acid sec-butyl ester 

Relevant articles and documents

Radical-mediated intramolecular β-C(sp3)-H amidation of alkylimidates: Facile synthesis of 1,2-amino alcohols

A new radical-mediated intramolecular β-C(sp3)-H amidation reaction of O-alkyl trichloro- or arylimidates is reported. Various oxazolines were efficiently prepared from easily accessible alcohol starting materials. The trichloro-oxazoline products can be hydrolyzed under mild conditions to give valuable 1,2-amino alcohols. This amidation reaction exhibits a broad substrate scope and good functional group tolerance, and offers a powerful means for the C(sp3)-H functionalization of alcohols. Mechanistic studies suggest that a sequence of 1,5-HAT of an imidate radical, iodination and cyclization might be operative.