131748-15-7 Usage
General Description
3-Methyl-5-(trifluoromethyl)pyridine is an organic compound with the chemical formula C7H6F3N. It is a clear, colorless liquid with a strong, sweet odor, and is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It is also used as a building block in the production of various chemical compounds. 3-Methyl-5-(trifluoromethyl)pyridine is considered to be a hazardous substance, with potential health risks associated with inhalation, skin contact, and ingestion. It should be handled with caution and appropriate safety measures.
Check Digit Verification of cas no
The CAS Registry Mumber 131748-15-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,7,4 and 8 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 131748-15:
(8*1)+(7*3)+(6*1)+(5*7)+(4*4)+(3*8)+(2*1)+(1*5)=117
117 % 10 = 7
So 131748-15-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H6F3N/c1-5-2-6(4-11-3-5)7(8,9)10/h2-4H,1H3
131748-15-7Relevant articles and documents
Trifluoromethylation of Arylsilanes with [(phen)CuCF3]
Morstein, Johannes,Hou, Haiyun,Cheng, Chen,Hartwig, John F.
supporting information, p. 8054 - 8057 (2016/09/13)
A method for the trifluoromethylation of arylsilanes is reported. The reaction proceeds with [(phen)CuCF3] as the CF3source under mild, oxidative conditions with high functional-group compatibility. This transformation complements prior trifluoromethylation of arenes in several ways. Most important, this method converts arylsilanes formed by the silylation of aryl C?H bonds to trifluoromethylarenes, thereby allowing the conversion of arenes to trifluoromethylarenes. The unique capabilities of the reported method are demonstrated by the conversion of a C?H bond into a C?CF3bond in active pharmaceutical ingredients which do not undergo this overall transformation by alternative functionalization processes, including a combination of borylation and trifluoromethylation.
