131749-24-1

Basic information

• Product Name: Nandrolone β-D-Glucuronide
• Synonyms: Nandrolone β-D-Glucuronide;17-β-Nandrolone glucuronide potassium salt;17-b-Nandrolone glucuronide potassium salt;(17β)-3-Oxoestr-4-en-17-yl β-D-Glucopyranosiduronic Acid;(17beta)-3-Oxoestr-4-en-17-yl beta-D-glucopyranosiduronic acid
• CAS NO: 131749-24-1
• Molecular Formula: C24H34O8
• Molecular Weight: 450.52196
• Product Categories: Glucuronides;Metabolites & Impurities;Steroids
• Mol File: 131749-24-1.mol

Chemical Properties

• Boiling Point: 683.953°C at 760 mmHg
• Flash Point: 233.74°C
• Appearance: /
• Density: 1.394g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.612
• CAS DataBase Reference: Nandrolone β-D-Glucuronide(CAS DataBase Reference)
• NIST Chemistry Reference: Nandrolone β-D-Glucuronide(131749-24-1)
• EPA Substance Registry System: Nandrolone β-D-Glucuronide(131749-24-1)

Safety Data

• Hazardous Substances Data: 131749-24-1(Hazardous Substances Data)

Usage

Uses

Metabolite of Nandrolone (N315000)

InChI:InChI=1/C24H34O8/c1-24-9-8-14-13-5-3-12(25)10-11(13)2-4-15(14)16(24)6-7-17(24)31-23-20(28)18(26)19(27)21(32-23)22(29)30/h10,13-21,23,26-28H,2-9H2,1H3,(H,29,30)/t13-,14+,15+,16-,17-,18-,19-,20-,21?,23+,24-/m0/s1

Upstream product

• 434-22-0 19-nortestosterone 
• 2616-64-0 UDP-glucuronic acid 
• 777038-38-7 α-D-glucuronyl fluoride 

Relevant articles and documents

The Escherichia coli glucuronylsynthase promoted synthesis of steroid glucuronides: Improved practicality and broader scope

A library of steroid glucuronides was prepared using the glucuronylsynthase derived from Escherichia coli β-glucuronidase, followed by purification using solid-phase extraction. A representative range of steroid substrates were screened for synthesis on t

Enzyme-assisted synthesis and structure characterization of glucuronide conjugates of eleven anabolic steroid metabolites

Enzyme-assisted in vitro synthesis of eleven glucuronide-conjugated anabolic androgenic steroid (AAS) metabolites was performed using biphenyl-induced rat liver microsomal enzymes. The substrates within the study were the main compounds and metabolites detected in human urine after dosing of, e.g. metandienone, metenolone, methyltestosterone, nandrolone, and testosterone. Yields of glucuronidation reactions were 13-28% for most compounds, but significantly higher (77-78%) for the substrates with 4-ene-3-one double bond system of the steroid A-ring. Characterization of glucuronide-conjugated AAS structures was based on nuclear magnetic resonance spectroscopy (1H NMR) and on liquid chromatographic-mass spectrometric (LC-MS) and tandem mass spectrometric (LC-MS/MS) analyses in positive and negative ion mode electrospray ionization (ESI). Only minor differences were observed in optimal synthesis conditions between various substrates, which offer a potential to apply this in vitro assay as a default method for glucuronidation of new AAS substrates. The method allowed for a rapid production pathway of stereochemically pure AAS glucuronides in milligram amount, such as needed, e.g. in the development of analytical methods in forensic or pharmaceutical sciences, as well as in doping control.