131758-91-3

Upstream product

• 123522-08-7 2,4-Dimethyl-4-(trifluoromethyl)-2-cyclohexen-1-ol 
• 66222-29-5 tri-n-butylstannylmethyl iodide 
• 123522-13-4 4-Iodomethyl-2-methyl-4-trifluoromethyl-cyclohex-2-enol 
• 123522-54-3 2-Methyl-4-(iodomethyl)-4-(trifluoromethyl)-2-cyclohexen-1-one 
• 123522-53-2 1-(Trifluoromethyl)-3-methyl-4-oxo-2-cyclohexene-1-methanol 
• 131758-87-7 2,2,2-Trifluoroethyl 1-(trifluoromethyl)-3-methyl-4-oxo-2-cyclohexene-1-carboxylate 

Downstream Products

• 123522-16-7 Trifluoro-β-cyclocitral 
• 123522-07-6 2,6-Dimethyl-6-trifluoromethyl-cyclohex-2-enecarbaldehyde 
• 123522-19-0 (2E,4E)-3-Methyl-5-(2,6-dimethyl-6-(trifluoromethyl)-1-cyclohexen-1-yl)-2,4-pentadienal 
• 123522-12-3 Methyl (2E,4E)-3-methyl-5-(2,6-dimethyl-6-(trifluoromethyl)-1-cyclohexen-1-yl)-2,4-pentadienoate 
• 123522-15-6 16,16,16-Trifluororetinal 
• 123522-20-3 Methyl 16,16,16-trifluororetinoate 
• 123522-18-9 (2E,4E)-5-(2,6-Dimethyl-6-trifluoromethyl-cyclohex-1-enyl)-3-methyl-penta-2,4-dien-1-ol 
• 123522-21-4 (2E,4E,6E,8E)-9-(2,6-Dimethyl-6-trifluoromethyl-cyclohex-1-enyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-ol 
• 123522-20-3 Methyl 16,16,16-trifluororetinoate 

Relevant academic research and scientific papers

Construction of Trifluoromethylated Quarternary Carbons via Diels-Alder Reactions of 2-(Trifluoromethyl)propenoic Acid Derivatives: Application to the Synthesis of 16,16,16-Trifluororetinal

Diels-Alder reactions of 2-(trifluoromethyl)propenoic acid (1) and its 2,2,2-trifluoroethyl ester 2 with various dienes gave adducts in good yields.In Lewis acid catalyzed Diels-Alder reactions of 2, the combination of the Lewis acid and solvent proved to

TRIFLUOROMETHYL GROUP ON QUATERNARY CARBON; SYNTHESIS OF 16,16,16-TRIFLUORORETINAL

The synthesis of racemic 16,16,16-trifluororetinal through the Diels-Alder reaction of 2-(trifluoromethyl)propenoic acid with functionalized diene is discussed.