131760-45-7 Usage
Uses
Used in Oncology:
(2alpha,5beta,7beta,10beta,13alpha)-4,10-bis(acetyloxy)-1,7-dihydroxy-13-[(2R)-2-hydroxy-3-phenylpropanoyl]oxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate is used as an anti-cancer agent for the treatment of various types of cancer, including breast, lung, and ovarian cancer. Its microtubule-stabilizing properties contribute to its effectiveness in inhibiting tumor growth and progression.
Used in Combination Chemotherapy:
This taxane compound is often administered in combination with other chemotherapy drugs to enhance the overall therapeutic effect and improve treatment outcomes for cancer patients. The acetyloxy and hydroxy groups on its structure likely contribute to its biological activity and pharmacokinetic properties, while the benzoate ester may play a role in enhancing its solubility and stability.
Check Digit Verification of cas no
The CAS Registry Mumber 131760-45-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,7,6 and 0 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 131760-45:
(8*1)+(7*3)+(6*1)+(5*7)+(4*6)+(3*0)+(2*4)+(1*5)=107
107 % 10 = 7
So 131760-45-7 is a valid CAS Registry Number.
131760-45-7Relevant academic research and scientific papers
Biologically Active Taxol Analogues with Deleted A-Ring Side Chain Substituents and Variable C-2' Configurations
Swindell, Charles S.,Krauss, Nancy E.,Horwitz, Susan B.,Ringel, Israel
, p. 1176 - 1184 (2007/10/02)
Taxol (1), a potent inhibitor of cell replication, enhances the assembly of tubulin into stable microtubules and promotes the formation of microtubule bundles in cells.In addition to its unique mechanism of action, taxol exhibits unusual promise as an ant
