131771-61-4

Basic information

• Product Name: 2H-Pyran-2-one, 5,6-dihydro-6-methyl-5-(phenylmethoxy)-, (5R,6S)-
• CAS NO: 131771-61-4
• Molecular Formula: C13H14O3
• Molecular Weight: 218.252
• Mol File: 131771-61-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2H-Pyran-2-one, 5,6-dihydro-6-methyl-5-(phenylmethoxy)-, (5R,6S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyran-2-one, 5,6-dihydro-6-methyl-5-(phenylmethoxy)-, (5R,6S)-(131771-61-4)
• EPA Substance Registry System: 2H-Pyran-2-one, 5,6-dihydro-6-methyl-5-(phenylmethoxy)-, (5R,6S)-(131771-61-4)

Safety Data

• Hazardous Substances Data: 131771-61-4(Hazardous Substances Data)

Upstream product

• 131771-60-3 (2S,3R,4R,5S,6S)-2-Benzenesulfonyl-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran 
• 131897-04-6 phenyl 2,3,4-tri-O-benzyl-1-thio-α-L-rhamnopyranoside 
• 183625-29-8 methyl (4R,5S)-4-benzyloxy-5-hydroxy-2(E)-hexenoate 
• 459809-85-9 (-)-(4R,5S)-4-benzyloxy-5-hydroxy-(2E)-hexenoic acid 
• 131870-59-2 1-(phenylsulfonyl)-3,4-di-O-benzyl-L-rhamnal 

Downstream Products

• 54826-92-5 (5R,6S)-5,6-dihydro-5-hydroxy-6-methylpyran-2-one 
• 1416448-90-2 C₁₄H₂₀O₄ 
• 1416448-92-4 C₁₄H₂₀O₄ 
• 1398599-96-6 O-benzyl-L-oleandropyranose 
• 1398599-97-7 O-benzyl-L-oleandropyranose 
• 928217-63-4 C₁₄H₁₈O₄ 
• 928217-61-2 C₁₄H₁₈O₄ 
• 866759-98-0 (4S,5S,1'S,2'S)-2-benzyl-5-(1'-benzyloxy-2'-hydroxy-propyl)-4-t-butyl-diphenylsiloxymethyl-isoxazolidine 
• 866759-85-5 (3aS,6R,7S,7aS)-2-benzyl-7-benzyloxy-6-methyl-4-oxo-tetrahydropyrano[3,4-d]isoxazolidine 

Relevant articles and documents

Synthesis of γ- and δ-lactone natural products by employing a trans-cis isomerization/lactonization strategy

Alkaline hydrolysis of 4-hydroxy- or/and 5-hydroxy-(2E)-alkenoate followed by acid treatment gave the corresponding (2E)-alkenoic acids which were subjected to lactone formation reaction without further purification. The crude acids were treated with 2,4,6-trichlorobenzoyl chloride in pyridine to afford ?-lactone or d-lactone, respectively, accompanied by trans-cis isomerization. By this procedure, (±)-(4,5)-trans-5-benzyloxy- 2-hexen-4-olide (90% overall yield), (S)-5-hydroxy-2-penten-4-olide (86% overall yield), (4S,5R)-5- hydroxy-2-hexen-4-olide (86% overall yield), (4R,5S)-5-hydroxy-2-hexen-4-olide (82% overall yield), (S)- parasorbic acid (58% overall yield) and natural product, (5R,7S)-7-hydroxy-2-octen-5-olide (euscapholide: 20% overall yield) were synthesized.

A Convenient Synthesis of Pyranoid Ene Lactones from Phenyl Glycosyl Sulfones

O-Benzyl protected pyranoid ene lactones (5,6-dihydro-2H-pyran-2-ones) 4a-c, 8 were obtained in high yield in a two-step procedure.Treatment of the phenyl glycosyl sulfones 2a-d, 6, which were readily prepared from their corresponding sulfides, with lithi