131792-18-2Relevant academic research and scientific papers
Novel Methodology for the Synthesis of trans-Alkene Dipeptide Isosteres
Shue, Youe-Kong,Carrera, George M.,Tufano, Michael D.,Nadzan, Alex M.
, p. 2107 - 2111 (2007/10/02)
Natural amino acids were converted to the corresponding allylic alcohols A, from which key precursors C were obtained via a three-step sequence .The allylic alcohols D were furt
AMIDE BOND SURROGATES: A GENERAL SYNTHETIC ROUTE TO TRANS CARBON-CARBON DOUBLE BOND ISOSTERES.
Shue, Youe-Kong,Carrera, George M.,Nadzan, Jr.,Nadzan, Alex M.
, p. 3225 - 3228 (2007/10/02)
A practical synthesis toward trans double bond replacements of amide bond pseudopeptides has been accomplished.This methodology provides a general route to a wide range of modified peptide analogs which may have biological significance.
