1318025-75-0 Usage
Uses
Used in Pharmaceutical Industry:
Chevalone B is used as a cytotoxic agent for its potential anticancer properties. It targets KB and NCI-H187 cancer cells, demonstrating its effectiveness in inhibiting the growth and proliferation of these cells.
Used in Drug Discovery and Development:
Chevalone B serves as a promising candidate for drug discovery and development due to its cytotoxic nature. Researchers can further investigate its mechanism of action and potential synergistic effects with other therapeutic agents to enhance its anticancer efficacy.
Used in Cancer Research:
Chevalone B is utilized in cancer research to study its cytotoxic effects on various cancer cell lines. This research can provide valuable insights into the compound's potential as a therapeutic agent and contribute to the development of novel cancer treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 1318025-75-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,8,0,2 and 5 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1318025-75:
(9*1)+(8*3)+(7*1)+(6*8)+(5*0)+(4*2)+(3*5)+(2*7)+(1*5)=130
130 % 10 = 0
So 1318025-75-0 is a valid CAS Registry Number.
1318025-75-0Relevant academic research and scientific papers
Bioactive meroterpenoids and alkaloids from the fungus Eurotium chevalieri
Kanokmedhakul, Kwanjai,Kanokmedhakul, Somdej,Suwannatrai, Ruchiruttikorn,Soytong, Kasem,Prabpai, Samran,Kongsaeree, Palangpon
supporting information; experimental part, p. 5461 - 5468 (2011/08/09)
Five new meroterpenoids, chevalones A-D (1-4), aszonapyrone B (8), and a new sequiterpene alkaloid, eurochevalierine (5), together with four known compounds, sequiterpene (6), terpenoid pyrrolobenzoxazine named CJ-12662 (7), meroterpenoid, aszonapyrone A (9), and ergosterol were isolated from the fungus Eurotium chevalieri. The structures were established on the basis of spectroscopic evidence. The configurations of 1 and 5 were determined by X-ray analysis. The biosynthetic pathway of 1-3, 8, and 9 were proposed. Chemical transformation of aszonapyrone A (9) was also studied. Compounds 4, 5, and 7 exhibited antimalarial activity against Plasmodium falciparum, while 3, 5, and 7 showed antimycobacterial activity against Mycobacterium tuberculosis. In addition, compounds 2-7 showed cytotoxicity against cancer cell lines.
