1318223-40-3Relevant academic research and scientific papers
In Situ Generated Palladium on Aluminum Phosphate as Catalytic System for the Preparation of β,β-Diarylated Olefins by Matsuda-Heck Reaction
Lucks, Sandra,Brunner, Heiko
, p. 1835 - 1842 (2017)
In situ generated palladium on aluminum phosphate provides a novel and active catalytic system for the preparation of β,β-diarylated olefins using the Matsuda-Heck reaction. The reaction conditions of this catalytic protocol were optimized by a Response-Surface model.
Facile synthesis of symmetrical 3,3-diarylacrylates by a Heck-Matsuda reaction: An expedient route to biologically active indanones
Taylor, Jason G.,Ribeiro, Rodrigo Da Silva,Correia, Carlos Roque D.
experimental part, p. 3861 - 3864 (2011/08/06)
A simple and straightforward synthesis of symmetrical 3,3-diarylacrylates based on a Heck-Matsuda reaction of arenediazonium salts bearing electron-donating groups with methylacrylates is described. The reaction employs Pd(OAc)2 as catalyst and goes to completion within 1 h affording the corresponding unsaturated diaryl esters in good to high yields. This method permitted the expeditious and efficient synthesis of the anticancer 3-arylindanone 5 in two operative steps in 43% overall yield.
