1318263-86-3Relevant academic research and scientific papers
Rational design of potent, small, synthetic allosteric inhibitors of thrombin
Sidhu, Preetpal Singh,Liang, Aiye,Mehta, Akul Y.,Abdel Aziz, May H.,Zhou, Qibing,Desai, Umesh R.
, p. 5522 - 5531 (2011)
Thrombin is a key enzyme targeted by the majority of current anticoagulants that are direct inhibitors. Allosteric inhibition of thrombin may offer a major advantage of finely tuned regulation. We present here sulfated benzofurans as the first examples of
