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(R,R)-(-)-2,2'-Isopropylidenebis(4-tert-butyl-2-oxazoline), also known as ITB, is a chiral ligand that plays a crucial role in asymmetric catalysis. It is characterized by its white to off-white solid appearance and a molecular formula of C18H31NO2, with a molecular weight of 297.45 g/mol. ITB is highly regarded for its high asymmetric induction and selectivity, making it an indispensable component in the synthesis of chiral catalysts and ligands, particularly for the production of pharmaceuticals and fine chemicals.

131833-97-1

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131833-97-1 Usage

Uses

Used in Pharmaceutical Industry:
(R,R)-(-)-2,2'-Isopropylidenebis(4-tert-butyl-2-oxazoline) is used as a chiral ligand for the synthesis of chiral catalysts and ligands, which are essential in the production of pharmaceuticals. Its high asymmetric induction and selectivity contribute to the creation of enantiomerically pure compounds, ensuring the desired biological activity and reducing potential side effects.
Used in Fine Chemicals Industry:
In the fine chemicals industry, (R,R)-(-)-2,2'-Isopropylidenebis(4-tert-butyl-2-oxazoline) serves as a key component in the preparation of chiral auxiliaries and ligands. These auxiliaries and ligands are vital for the synthesis of optically active compounds, which are crucial in various applications, including fragrances, agrochemicals, and specialty materials.
Used in Asymmetric Synthesis:
(R,R)-(-)-2,2'-Isopropylidenebis(4-tert-butyl-2-oxazoline) is used as a chiral ligand in asymmetric synthesis, a technique that allows for the selective formation of one enantiomer over another. This selective synthesis is crucial in producing enantiomerically pure compounds, which are essential for various applications, including the development of new drugs and the synthesis of chiral compounds with specific properties.
Used in Research and Development:
ITB is also utilized in research and development for the discovery and optimization of new asymmetric catalytic systems. Its high asymmetric induction and selectivity make it a valuable tool for chemists to explore novel reactions and develop more efficient and selective synthetic routes for the production of chiral compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 131833-97-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,8,3 and 3 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 131833-97:
(8*1)+(7*3)+(6*1)+(5*8)+(4*3)+(3*3)+(2*9)+(1*7)=121
121 % 10 = 1
So 131833-97-1 is a valid CAS Registry Number.

131833-97-1 Well-known Company Product Price

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  • TCI America

  • (I0795)  (R,R)-(+)-2,2'-Isopropylidenebis(4-tert-butyl-2-oxazoline)  >98.0%(GC)

  • 131833-97-1

  • 100mg

  • 3,450.00CNY

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131833-97-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name (R,R)-(+)-2,2'-Isopropylidenebis(4-tert-butyl-2-oxazoline)

1.2 Other means of identification

Product number -
Other names (R,R)-(+)-2,2-Bis(4-tert-butyl-2-oxazolin-2-yl)propane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:131833-97-1 SDS

131833-97-1Downstream Products

131833-97-1Relevant academic research and scientific papers

Asymmetric hetero-Diels-Alder Reaction of trans-1-Methoxy-3-trimethylsilyloxy-buta-1,3-diene Catalyzed by Zinc Complexes

Buda, Szymon,Mlynarski, Jacek,Stefaniak, Matylda

, (2020/08/21)

Asymmetric hetero-Diels-Alder reactions of Danishefsky's diene and glyoxylate/pyruvate esters catalyzed by readily available zinc triflate complex with BOX ligand afforded the corresponding adduct which upon treatment with trifluoroacetic acid furnished the hetero-Diels-Alder product in 91 % enantiomeric excess and 87 % isolated yield. This reaction was applied to the concise synthesis of six-membered ulosonic acid C-glycoside.

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