131843-10-2Relevant academic research and scientific papers
Regio- and Stereo-selectivity in CuI-Catalyzed Grignard Reactions with tert-Butyl(Z)-β-Tosyloxy α,β-Enoates
Jalander, Lars,Oksanen, Lasse,Rosling, Ari
, p. 842 - 844 (2007/10/02)
Alkyl (Z)-β-tosyloxy-α,β-enoates (1a-h) have been converted into alkyl β-alkyl-α,β-enoates (2a-h) by CuI-catalyzed Grignard reactions.The vinylic addition-elimination reactions proceeded almost exclusively with retention of configuration.
