13185-87-0

Basic information

• Product Name: N-benzoyl-β-D-neuraminic acid
• CAS NO: 13185-87-0
• Molecular Weight: 371.344
• Mol File: 13185-87-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzoyl-β-D-neuraminic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzoyl-β-D-neuraminic acid(13185-87-0)
• EPA Substance Registry System: N-benzoyl-β-D-neuraminic acid(13185-87-0)

Safety Data

• Hazardous Substances Data: 13185-87-0(Hazardous Substances Data)

Upstream product

• 93-97-0 benzoic acid anhydride 
• 90-76-6 2-deoxy-2-amino glucose 
• 6847-14-9 N-benzoyl-D-glucosamine 

Relevant articles and documents

Biological properties of N-acyl and N-haloacetyl neuraminic acids: Processing by enzymes of sialic acid metabolism, and interaction with influenza virus

Several unnatural N-acyl neuraminic acids (N-propionyl, N-hexanoyl, N-benzoyl, N-trifluoroacetyl, N-chloroacetyl, N-difluoroacetyl) were prepared enzymatically using immobilised sialic acid aldolase. N-Trifluoroacetyl-, N-chloroacetyl- and N-difluoroacetyl neuraminic acids were shown to enhance up to 10-fold the rate of association of influenza virus A to a sialoglycolipid neomembrane by surface plasmon resonance, and were found to act as weak inhibitors (Kiapp 0.45-2.0 mM) of influenza virus neuraminidase. The N-propionyl, N-chloroacetyl- and N-difluoroacetyl neuraminic acids were found to be substrates for recombinant Escherichia coli CMP sialate synthase, to give the corresponding CMP-N-acyl-neuraminic acids. CMP-N-propionyl neuraminic acid was found not to be a substrate for CMP-N-acetyl neuraminic acid hydroxylase from pig submandibular gland. Copyright