Cas 1318641-60-9,(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(1S,2S)-1-benzyl-3-chloro-2-hydroxypropyl]carbamate

1318641-60-9

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Basic information

Product Name: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(1S,2S)-1-benzyl-3-chloro-2-hydroxypropyl]carbamate
Synonyms: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(1S,2S)-1-benzyl-3-chloro-2-hydroxypropyl]carbamate
CAS NO:1318641-60-9
Molecular Formula:
Molecular Weight: 355.818
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(1S,2S)-1-benzyl-3-chloro-2-hydroxypropyl]carbamate(CAS DataBase Reference)
NIST Chemistry Reference: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(1S,2S)-1-benzyl-3-chloro-2-hydroxypropyl]carbamate(1318641-60-9)
EPA Substance Registry System: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(1S,2S)-1-benzyl-3-chloro-2-hydroxypropyl]carbamate(1318641-60-9)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1318641-60-9(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1318641-60-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,8,6,4 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1318641-60:
(9*1)+(8*3)+(7*1)+(6*8)+(5*6)+(4*4)+(3*1)+(2*6)+(1*0)=149
149 % 10 = 9
So 1318641-60-9 is a valid CAS Registry Number.

1318641-60-9Upstream product

1318641-60-9Downstream Products

206361-99-1 darunavir

1318641-60-9Relevant academic research and scientific papers

PROCESS FOR THE PREPARATION OF DARUNAVIR AND DARUNAVIR INTERMEDIATES

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, (2011/08/21)

The present invention relates to a process for the preparation of darunavir, a nonpeptide protease inhibitor (PI), useful for the treatment of HIV/AIDS patients harboring multidrug-resistant HIV-1 variants that do not respond to previously existing HAART regimens. The present invention further relates to processes for the stereo-directed preparation of darunavir intermediates, in particular (3R,3aS,6aR)-hexahydrofuro [2,3-b] furan-3-ol and to certain novel intermediates obtained by such processes.

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