1318759-10-2

Upstream product

• 124957-46-6 (2E,4E)-methyl 2-acetoxymethyl-5-phenyl-penta-2,4-dienoate 
• 124957-40-0 (E)-methyl 3-acetoxy-2-methylene-5-phenyl-pent-4-enoate 
• 124575-69-5 methyl (4E)-3-hydroxy-2-methylene-5-phenylpent-4-enoate 
• 1318759-09-9 (2S,3R,αR)-6-oxo-1-(α-methylbenzyl)-piperidine-2,3-dicarboxylic acid 3-methyl ester 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 1318759-08-8 (2S,3R,αR)-methyl 2-formyl-6-oxo-1-(α-methylbenzyl)-piperidine-3-carboxylate 
• 1318759-07-7 (2R,3R,αR,E)-methyl 6-oxo-1-(α-methylbenzyl)-2-styrylpiperidine-3-carboxylate 
• 1318759-06-6 (4R,5R,αR,E)-4-methoxycarbonyl-5-(N-α-methylbenzylamino)-7-phenyl-hept-6-enoic acid 

Downstream Products

• 1318759-11-3 (2S,3R,αR)-dimethyl 1-(α-methylbenzyl)-piperidine-2,3-dicarboxylate 

Relevant academic research and scientific papers

Enantioselective synthesis of cis-(2S,3R)- and trans-(2S,3S)- piperidinedicarboxylic acids using domino: Allylic acetate and Ireland-Claisen rearrangements and Michael addition as the key steps

An enantioselective synthesis of (2S,3R)-piperidine-2,3-dicarboxylic acid and (2S,3S)-piperidine-2,3-dicarboxylic acid is described. This synthesis was mainly based on a δ-amino acid formation via a domino reaction: allylic acetate rearrangement, stereose