1318795-24-2

Basic information

• Product Name: (S(S),S(S),2S)-1,1-bis-p-tolylsulfinyl-2-ethoxy-2-phenylethane
• Synonyms: (S(S),S(S),2S)-1,1-bis-p-tolylsulfinyl-2-ethoxy-2-phenylethane
• CAS NO: 1318795-24-2
• Molecular Weight: 426.601
• Mol File: 1318795-24-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S(S),S(S),2S)-1,1-bis-p-tolylsulfinyl-2-ethoxy-2-phenylethane(CAS DataBase Reference)
• NIST Chemistry Reference: (S(S),S(S),2S)-1,1-bis-p-tolylsulfinyl-2-ethoxy-2-phenylethane(1318795-24-2)
• EPA Substance Registry System: (S(S),S(S),2S)-1,1-bis-p-tolylsulfinyl-2-ethoxy-2-phenylethane(1318795-24-2)

Safety Data

• Hazardous Substances Data: 1318795-24-2(Hazardous Substances Data)

Upstream product

• 2388-07-0 lithium ethoxide 
• 443640-88-8 (S_S,S_S)-2-phenyl-1,1-di-p-tolylsulfinyl-ethylene 
• 64-17-5 ethanol 

Relevant articles and documents

Conjugate additions to alkylidene bis(sulfoxides)

A general study on the conjugate addition of anionic nucleophiles to alkylidene bis(sulfoxides) is presented. Alkoxides gave high yielding and diastereoselective addition reactions, which could be influenced by solvents and the counteranion. Azides provided an interesting entry into sulfinyl-substituted triazoles. Organometallics, mainly copper reagents, proved also to be valuable nucleophiles, and complete inversion of the stereoselectivity was achieved in the addition reaction with the latter. Modelizations provide a rationale for the observed diastereoselectivity. Taking the Michael: Alkylidene bis(sulfoxides) are exquisite Michael acceptors toward a broad series of nucleophiles, and in most cases the reaction affords the adducts in high yields with complete diastereoselectivity.