1318800-16-6

Basic information

• Product Name: (1R,2R,3S,4S)-2-(acetoxymethyl)-3-(tosyloxymethyl)-7-azabicyclo[2.2.1]heptane hydrochloride
• Synonyms: (1R,2R,3S,4S)-2-(acetoxymethyl)-3-(tosyloxymethyl)-7-azabicyclo[2.2.1]heptane hydrochloride
• CAS NO: 1318800-16-6
• Molecular Weight: 389.9
• Mol File: 1318800-16-6.mol

Chemical Properties

• CAS DataBase Reference: (1R,2R,3S,4S)-2-(acetoxymethyl)-3-(tosyloxymethyl)-7-azabicyclo[2.2.1]heptane hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R,3S,4S)-2-(acetoxymethyl)-3-(tosyloxymethyl)-7-azabicyclo[2.2.1]heptane hydrochloride(1318800-16-6)
• EPA Substance Registry System: (1R,2R,3S,4S)-2-(acetoxymethyl)-3-(tosyloxymethyl)-7-azabicyclo[2.2.1]heptane hydrochloride(1318800-16-6)

Safety Data

• Hazardous Substances Data: 1318800-16-6(Hazardous Substances Data)

Upstream product

• 1318800-13-3 tert-butyl (2R,3S)-2,3-bis(hydroxymethyl)-7-azabicyclo[2.2.1]heptane-7-carboxylate 
• 1318800-15-5 (1R,2R,3S,4S)-2-(acetoxymethyl)-3-(hydroxymethyl)-7-(tert-butoxycarbonyl)-7-azabicyclo[2.2.1]heptane 
• 98-59-9 p-toluenesulfonyl chloride 
• 378245-82-0 dimethyl 7-aza-N-tert-butoxycarbonylbicyclo[2.2.1]heptane-2-endo,3-endo-dicarboxylate 

Relevant articles and documents

Chemoenzymatic enantioselective synthesis of 7-azabicyclo[2.2.1]heptane derivatives

The enantioselective acylation (desymmetrization) of meso-7-azabicyclo[2.2. 1]heptanediol 2 by vinyl acetate in the presence of Candida antarctica lipase B gave the corresponding (1R,2R,3S,4S)-monoester 4 in high enantiomeric purity (ee ≥ 98%).