131882-15-0Relevant articles and documents
Sterically Hindered Bases. Synthesis of 2,4,6-Trisubstituted Pyrimidines
Martinez, A. Garcia,Fernandez, A. Herrera,Alvarez, Roberto Martinez,Losada, M. C. Silva,Vilchez, D. Molero,et al.
, p. 881 - 882 (1990)
A new method for the synthesis of sterically hindered pyrimidines 7 by the reaction of alkynes 5 with nitriles 6 in the presence of trifluoromethanesulfonic acid is described.The pKa*-values of some of the synthesized pyrimidines 7, which can b