13190-50-6

Basic information

• Product Name: [p-(dimethylamino)phenyl]lithium
• Synonyms: [p-(dimethylamino)phenyl]lithium;[4-(Dimethylamino)phenyl]lithium;4-(Dimethylamino)phenyllithium;N,N-Dimethyl-4-lithioaniline;Einecs 236-146-9
• CAS NO: 13190-50-6
• Molecular Formula: C₈H₁₀LiN
• Molecular Weight: 127.1127
• EINECS: 236-146-9
• Mol File: 13190-50-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [p-(dimethylamino)phenyl]lithium(CAS DataBase Reference)
• NIST Chemistry Reference: [p-(dimethylamino)phenyl]lithium(13190-50-6)
• EPA Substance Registry System: [p-(dimethylamino)phenyl]lithium(13190-50-6)

Safety Data

• Hazardous Substances Data: 13190-50-6(Hazardous Substances Data)

Usage

General Description

[p-(dimethylamino)phenyl]lithium is a chemical compound with the formula C8H11NLi. It is an organolithium reagent used in organic synthesis as a strong base and nucleophile. The compound consists of a phenyl group substituted with a dimethylamino group and a lithium atom attached to the phenyl ring. [p-(dimethylamino)phenyl]lithium is highly reactive and can be used in various reactions such as metalation, cross-coupling, and addition reactions. It is important to handle [p-(dimethylamino)phenyl]lithium with caution due to its air and moisture sensitivity, and it is typically stored and handled under inert atmospheres or in dry solvents.

InChI:InChI=1/C8H10N.Li/c1-9(2)8-6-4-3-5-7-8;/h4-7H,1-2H3;/rC8H10LiN/c1-10(2)8-5-3-7(9)4-6-8/h3-6H,1-2H3

Upstream product

• 586-77-6 4-bromo-N,N-dimethylaniline 
• 109-72-8 n-butyllithium 
• 121-69-7 N,N-dimethyl-aniline 

Downstream Products

• 100381-45-1 N,N-dimethyl-4-(pyridin-2-yl)aniline 
• 16032-41-0 2-(4-(dimethylamino)phenyl)quinoline 
• 32564-93-5 4-(isoquinolin-1-yl)-N,N-dimethylaniline 
• 30479-24-4 N,N-dimethyl-4-(7-methyl-quinolin-2-yl)-aniline 
• 30479-21-1 dimethyl[4-(6-methylquinolin-2-yl)phenyl]amine 
• 102079-39-0 N,N-dimethyl-4-[4,7]phenanthrolin-3-yl-aniline 
• 113493-38-2 9,10-bis-(4-dimethylamino-phenyl)-9,10-dihydro-anthracene-9,10-diol 
• 16087-24-4 N,N-dimethyl-4-(trimethylsilyl)aniline 
• 102319-88-0 1,1-bis-(4-dimethylamino-phenyl)-propane-1,2-diol 
• 1719-05-7 (4-dimethylamino-phenyl)-diphenyl-methanol 
• 17881-31-1 methyl-4-(dimethylamino)phenyldichlorosilane 
• 18418-79-6 4-(triethoxysilyl)-N,N-dimethylaniline 
• 1521-20-6 (ph-4-Nme₂)3SiOH 
• 18586-44-2 (ph-4-Nme₂)2Si(Oet)2 

Relevant articles and documents

CATALYTIC RADIOFLUORINATION

One aspect of the present invention relates to a method of preparing radio fluorinated substituted alkyl, cycloalkyl, aryl, and alkenyl compounds. In a preferred embodiment, potassium fluoride-18 is used. Another aspect of the invention relates to arylammonium compounds containing fluorine-18 that are useful as imaging agents. In certain embodiments, the ammonium compound is a tetraaryl ammonium salt. Another aspect of the invention relates to arylsulfonium compounds containing fluorine-18 that are useful as imaging agents. In certain embodiments, the sulfonium compound is a triaryl sulfonium salt. Another aspect of the present invention relates to a method of obtaining a positron emission image of a mammal, comprising the steps of administering to a mammal a compound of the invention, and acquiring a positron emission spectrum of the mammal.