131900-62-4 Usage
General Description
(3R)-(+)-3-Acetamidopyrrolidine is a chemical compound with the molecular formula C7H13NO. It is a chiral molecule, with a specific three-dimensional arrangement of atoms that gives it a unique pharmacological profile. (3R)-(+)-3-Acetamidopyrrolidine is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its applications include the production of certain drugs, such as antivirals and analgesics. (3R)-(+)-3-Acetamidopyrrolidine's stereochemistry makes it a valuable building block for the preparation of enantiomerically pure compounds, which are often important in the development of new pharmaceuticals. Its properties and applications make it a key component in the chemical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 131900-62-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,9,0 and 0 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 131900-62:
(8*1)+(7*3)+(6*1)+(5*9)+(4*0)+(3*0)+(2*6)+(1*2)=94
94 % 10 = 4
So 131900-62-4 is a valid CAS Registry Number.
131900-62-4Relevant articles and documents
Asymmetric Synthesis and Properties of the Enantiomers of the Antibacterial Agent 7-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Hydrochloride
Rosen, Terry,Chu, Daniel T. W.,Lico, Isabella M.,Fernandes, Prabhavathi B.,Shen, Linus,et al.
, p. 1586 - 1590 (2007/10/02)
Compound 1 is a potent member of the quinoloecarboxylic acid class of antibacterial agents and is currently undergoing clinical evaluation.We have developed efficient asymmetric syntheses of the enantiomers of this agent.The S-(+) enantiomer 1a is 1-2 log2 dilutions more active than the R-(-) enantiomer 1b against aerobic bacteria and 1-2 or more log2 dilutions more active against anaerobic bacteria in vitro.The enantiomer 1a shows significantly better in vivo activity in a Pseudomonas aeruginosa mouse protection model compared to racemic 1.Coupled with the improved solubility profile of 1a relative to racemic material, these features may be of practical significance from a clinical standpoint.