131918-62-2
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Basic information
- Product Name: 19-nor-Doxercalciferol
- Synonyms: 19-nor-Doxercalciferol;(1R,3R)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]cyclohexane-1,3-diol
- CAS NO:131918-62-2
- Molecular Formula: C27H44O2
- Molecular Weight: 400.63706
- EINECS: N/A
- Product Categories: N/A
- Mol File: 131918-62-2.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 19-nor-Doxercalciferol(CAS DataBase Reference)
- NIST Chemistry Reference: 19-nor-Doxercalciferol(131918-62-2)
- EPA Substance Registry System: 19-nor-Doxercalciferol(131918-62-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 131918-62-2(Hazardous Substances Data)
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131918-62-2 Usage
Type of compound
Synthetic analog of the active form of vitamin D (calcitriol)Indications
Treatment of secondary hyperparathyroidism in patients with chronic kidney disease, and management of hypocalcemia in patients undergoing chronic renal dialysisChemical structure modification
Removal of the carbon atom at the 19th position from the parent compound doxercalciferolEffect on calcium and phosphorus metabolism
Enhances the drug's ability to regulate calcium and phosphorus metabolism without significantly affecting the levels of calcium in the bloodMechanism of action
Acts as a vitamin D receptor agonistImpact on gastrointestinal absorption
Promotes the absorption of calcium and phosphorus from the gastrointestinal tractEffect on parathyroid hormone secretion
Reduces the secretion of parathyroid hormonePurpose
Helps to maintain healthy mineral levels in the bodyImportance
An important therapeutic agent for managing mineral imbalances in patients with chronic kidney diseaseCheck Digit Verification of cas no
The CAS Registry Mumber 131918-62-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,9,1 and 8 respectively; the second part has 2 digits, 6 and 2 respectively.Calculate Digit Verification of CAS Registry Number 131918-62:
(8*1)+(7*3)+(6*1)+(5*9)+(4*1)+(3*8)+(2*6)+(1*2)=122
122 % 10 = 2
So 131918-62-2 is a valid CAS Registry Number.
131918-62-2Upstream product
131918-62-2Downstream Products
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19-nor-Doxercalciferol
