1319211-60-3

Upstream product

• 50866-82-5 2,3:4,5-di-O-isopropylidene-aldehydo-D-ribose 
• 1319211-62-5 (4R,4'R,5R)-5-(bis(isopropylthio)methyl)-2,2,2',2'-tetramethyl-4,4'-bi(1,3-dioxolane) 
• 1319211-61-4 (Z)-1-phenyl-N-(((4S,4'R,5S)-2,2,2',2'-tetramethyl-4,4'-bi(1,3-dioxolan)-5-yl)methylene)methanamine N-oxide 
• 292638-85-8 acrylic acid methyl ester 
• 1071695-98-1 (2R,3R,4R)-5,5-bis(isopropylthio)pentane-1,2,3,4-tetraol 
• 532-20-7 D-Ribose 
• 622-30-0 N-benzyl hydroxylalmine 

Downstream Products

• 1319211-72-7 (3aR,4S,8aS,8bS)-5-benzyl-4-((tert-butyldimethylsilyloxy)methyl)-2,2-dimethyloctahydro-[1,3]dioxolo[4,5-a]pyrrolizin-5-ium chloride 
• 1319211-65-8 (S)-1-benzyl-5-((4S,4'R,5S)-2,2,2',2'-tetramethyl-4,4'-bi(1,3-dioxolan)-5-yl)pyrrolidin-2-one 
• 1319211-67-0 1-benzyl-2-((4S,4'R,5S)-2,2,2',2'-tetramethyl-4,4'-bi(1,3-dioxolan)-5-yl)pyrrolidine 
• 1319211-69-2 (1R)-1-((4R,5S)-5-(1-benzylpyrrolidin-2-yl)-2,2-dimethyl-1,3-dioxolan-4-yl)ethane-1,2-diol 
• 1319211-71-6 (1R)-1-((4R,5S)-5-(1-benzylpyrrolidin-2-yl)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-(tert-butyldimethylsilyloxy)ethanol 

Relevant academic research and scientific papers

Synthesis of trihydroxylated pyrrolizidine and indolizidine alkaloids based on SmI2-induced reductive coupling of chiral nitrones with methyl acrylate

Synthesis of trihydroxylated pyrrolizidines, the enantiomer of 2-epihyacinthacine A2 and indolizidine analogues of the natural alkaloids is reported. The key step of these syntheses is the stereoselective samarium diodide-induced coupling of th