131922-07-1 Usage
Description
(1,4-Dimethylpiperazin-2-yl)methylamine, also known as DMAPA, is a chemical compound with a purity of 97%. It is a versatile intermediate used in the synthesis of various pharmaceuticals and agrochemicals. DMAPA is a potent and selective inhibitor of granulocyte colony-stimulating factor and has been investigated for its potential in treating various inflammatory diseases. It is also used as a building block in the production of specialty chemicals and advanced materials. DMAPA is known for its stability and high reactivity, making it a valuable compound in the field of organic chemistry.
Used in Pharmaceutical Industry:
(1,4-Dimethylpiperazin-2-yl)methylamine, 97% is used as an intermediate in the synthesis of various pharmaceuticals for its versatility and reactivity.
Used in Agrochemical Industry:
(1,4-Dimethylpiperazin-2-yl)methylamine, 97% is used as an intermediate in the synthesis of various agrochemicals for its versatility and reactivity.
Used in Specialty Chemicals Production:
(1,4-Dimethylpiperazin-2-yl)methylamine, 97% is used as a building block in the production of specialty chemicals for its stability and high reactivity.
Used in Advanced Materials Production:
(1,4-Dimethylpiperazin-2-yl)methylamine, 97% is used as a building block in the production of advanced materials for its stability and high reactivity.
Used in Inflammatory Disease Treatment Research:
(1,4-Dimethylpiperazin-2-yl)methylamine, 97% is used as a potent and selective inhibitor of granulocyte colony-stimulating factor for its potential in treating various inflammatory diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 131922-07-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,9,2 and 2 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 131922-07:
(8*1)+(7*3)+(6*1)+(5*9)+(4*2)+(3*2)+(2*0)+(1*7)=101
101 % 10 = 1
So 131922-07-1 is a valid CAS Registry Number.
131922-07-1Relevant articles and documents
Development of potent serotonin-3 (5-HT3) receptor antagonists. I. Structure-activity relationships of 2-alkoxy-4-amino-5-chlorobenzamide derivatives
Harada,Morie,Hirokawa,Yoshida,Kato
, p. 1364 - 1378 (2007/10/02)
A new series of 2-alkoxy-4-amino-5-chlorobenzamide derivatives hearing five- to seven-membered heteroalicyclic rings in the amine moiety was synthesized and evaluated for serotonin-3 (5-HT3) receptor antagonistic activity by assaying the ability to antagonize the yon Bezold-Jarisch reflex in rats. The five- to seven-membered heteroalicycles comprise pyrrolidine, morpholine, 1,4-thiazine, piperidine, piperazine, 1,4-oxazepine, 1,4- thiazepine, azepine, and 1,4-diazepine rings. Among them, some benzamide derivatives having a 1,4-diazepine ring showed a potent 5-HT3 receptor antagonistic activity. In particular, 4-amino-5-chloro-N-(1,4- dimethylhexahydro-1H-1,4-diazepin-6-yl)-2-ethoxyhenzamide (96) and the 1- benzyl-4-methylhexahydro-1H-1,4-diazepine analogue 103 showed potent 5-HT3 receptor antagonistic activity without 5-HT4 receptor binding affinity.
