131926-45-9

Basic information

• Product Name: 3-Methyl-2-oxo-1-oxa-spiro[4.5]dec-3-ene-4-carboxylic acid [4-(benzyl-methyl-amino)-but-2-ynyl]-amide
• CAS NO: 131926-45-9
• Molecular Weight: 380.487
• Mol File: 131926-45-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Methyl-2-oxo-1-oxa-spiro[4.5]dec-3-ene-4-carboxylic acid [4-(benzyl-methyl-amino)-but-2-ynyl]-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methyl-2-oxo-1-oxa-spiro[4.5]dec-3-ene-4-carboxylic acid [4-(benzyl-methyl-amino)-but-2-ynyl]-amide(131926-45-9)
• EPA Substance Registry System: 3-Methyl-2-oxo-1-oxa-spiro[4.5]dec-3-ene-4-carboxylic acid [4-(benzyl-methyl-amino)-but-2-ynyl]-amide(131926-45-9)

Safety Data

• Hazardous Substances Data: 131926-45-9(Hazardous Substances Data)

Upstream product

• 617-52-7 Dimethyl itakonate 
• 108-94-1 cyclohexanone 
• 50-00-0 formaldehyd 
• 131926-38-0 Cyclohexane-5-spiro-3-methyl-4-N-(2'-propynyl)carboxamido-2-oxo-2,5-dihydrofurane 
• 103-67-3 benzyl-methyl-amine 
• 58887-89-1 3-methyl-2-oxo-1-oxa-spiro[4.5]dec-3-ene-4-carbonyl chloride 
• 29542-72-1 Cyclohexane-5-spiro-3-methyl-2-oxo-2,5-dihydrofurane-4-carboxylic acid 
• 29542-73-2 methyl 9-methyl-8-oxo-7-oxaspiro[5,4]dec-9-ene-10-carboxylate 

Relevant articles and documents

Synthesis of acetylenic spirobutenolide derivatives and evaluation of their growth inhibitory effect on cells in culture

Acetylenic spirobutenolide amides and esters and their Mannich bases were synthesized to evaluate their growth inhibitory effect. The biological tests have used both normal and transformed cells and they have shown the selectivity of the prepared compounds. The ester derivatives presented the best selectivity comparable to that of daunorubicin.