131926-96-0

Basic information

• Product Name: 5-Hydroxy Lansoprazole Sulfide
• Synonyms: 5-Hydroxy Lansoprazole Sulfide
• CAS NO: 131926-96-0
• Molecular Formula: C16H13F3N3O2S
• Molecular Weight: 368.3535296
• Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Sulfur & Selenium Compounds;Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
• Mol File: 131926-96-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 110-112 °C
• Boiling Point: 547.5±60.0 °C(Predicted)
• Appearance: /
• Density: 1.49±0.1 g/cm3(Predicted)
• Storage Temp.: Refrigerator
• Solubility: DMSO, Methanol (Slightly)
• PKA: 8.55±0.40(Predicted)
• CAS DataBase Reference: 5-Hydroxy Lansoprazole Sulfide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Hydroxy Lansoprazole Sulfide(131926-96-0)
• EPA Substance Registry System: 5-Hydroxy Lansoprazole Sulfide(131926-96-0)

Safety Data

• Hazardous Substances Data: 131926-96-0(Hazardous Substances Data)

Relevant articles and documents

Microwave synthesis of lansoprazole drug intermediate

The sulfide intermediate, (′2-[[[3-Methyl-4- (2,2,2-trifluoroethoxy)- 2-pyridinyl] methyl] thio]-1H-benzimidazole) (3), required for the industrial synthesis of the anti-ulcer drug Lansoprazole, has been prepared in excellent yields by microwave irradiation of a dry mixture of 2-chloromethyl-3-methyl-4- (2,2,2-trifluoroethoxy)pyridine hydrochloride (1) and 2-mercaptobenzimidazole (2) in the presence of Na2CO3.