131929-40-3Relevant academic research and scientific papers
Diastereofacial Selection in Titanium Tetrachloride-Promoted Aldol Reactions with the Silyl Ketene Acetal of Methyl (R)-3-Hydroxybutanoate
Shirai, Fumiyuki,Gu, Jin-Hua,Nakai, Takeshi
, p. 1931 - 1934 (2007/10/02)
The title reaction is shown to exhibit a high level of "anti" diastereofacial selection, in contrast to the "syn" selection observed for the reaction with the dilithium enolate of the chiral ester.Mechanistic grounds for the "anti" stereoselection are dis
