131942-55-7

Basic information

• Product Name: 2-(diethylamino)-7-ethoxychromone
• Synonyms: 2-(diethylamino)-7-ethoxychromone
• CAS NO: 131942-55-7
• Molecular Formula: C₁₅H₁₉NO₃
• Molecular Weight: 0
• Mol File: 131942-55-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 377.5°Cat760mmHg
• Flash Point: 182.1°C
• Appearance: /
• Density: 1.14g/cm³
• Vapor Pressure: 6.74E-06mmHg at 25°C
• Refractive Index: 1.56
• CAS DataBase Reference: 2-(diethylamino)-7-ethoxychromone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(diethylamino)-7-ethoxychromone(131942-55-7)
• EPA Substance Registry System: 2-(diethylamino)-7-ethoxychromone(131942-55-7)

Safety Data

• Hazardous Substances Data: 131942-55-7(Hazardous Substances Data)

Usage

General Description

2-(diethylamino)-7-ethoxychromone is a chemical compound that belongs to the chromone family. It is an organic compound with a yellow crystalline appearance at room temperature. This chemical has potential pharmaceutical applications, as it has been studied for its anti-inflammatory and antioxidant properties. It is also used in the synthesis of other organic compounds and in research as a fluorescent probe. Additionally, 2-(diethylamino)-7-ethoxychromone has been investigated for its potential role in the treatment of various diseases, including cancer and neurodegenerative disorders. Overall, this compound has garnered interest in the scientific community for its diverse potential applications.

InChI:InChI=1/C15H19NO3/c1-4-16(5-2)15-10-13(17)12-8-7-11(18-6-3)9-14(12)19-15/h7-10H,4-6H2,1-3H3

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Relevant articles and documents

Synthesis and antiplatelet activity of 2-(diethylamino)-7-ethoxychromone and related compounds

2-(Diethylamino)-7-ethoxychromone 3a and its 2-(1-piperidinyl)analogue 3b were synthesized by reaction of 3-ethoxyphenol 1 with 3-(dialkylamino)-3-oxo-propanoic acid ethyl ester 2 in the presence of phosphorus oxychloride.With a view to improve their biological activity the above 7-ethoxychromones 3 were submitted to some structural modifications firstly involving the 4-CO group.The 4H-chromenes 4 and the 4-thiochromones 5 were obtained by action of suitable reagents.The compounds 5 were then easily transformed to 4-(methylthio)chromenylium iodides 6.Then from the 2-(diethylamino)-7-ethoxychromone 3a were obtained with suitable reactions the 3,6-diamino derivative 8, the 3- and 6-formyl derivatives 9a,b and the Mannich base 10.By action of acetic anhydride this latter compound yielded the methylenebis derivative 11.Most of the above compounds were tested in vitro for their inhibitory activities against human platelet aggregation induced by collagen, ADP and arachidonic acid.Among the tested compounds the 2-(diethylamino)-7-ethoxychromone 3a showed the highest activity.