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(E/Z)-FK-506 26,28-Allylic Ester Rearrangement Impurity is a chemical compound derived from the thermal rearrangement of the immunosuppressant FK-506. It is a white to pale yellow solid and is considered an impurity in the production of FK-506.

131944-48-4

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131944-48-4 Usage

Uses

Used in Pharmaceutical Industry:
(E/Z)-FK-506 26,28-Allylic Ester Rearrangement Impurity is used as a research compound for understanding the chemical properties and behavior of FK-506 and its derivatives. This knowledge can be applied to improve the synthesis and purification processes of FK-506, leading to a higher quality and more effective immunosuppressant drug.
Additionally, the study of this impurity can provide insights into the potential side effects or interactions that may occur when using FK-506 as a medication, allowing for better management and treatment of patients undergoing immunosuppressive therapy.
Used in Chemical Research:
(E/Z)-FK-506 26,28-Allylic Ester Rearrangement Impurity can also be used as a subject of study in chemical research, particularly in the fields of organic chemistry and medicinal chemistry. Researchers can investigate the structural and functional properties of (E/Z)-FK-506 26,28-Allylic Ester RearrangeMent IMpurity, as well as explore its potential applications in various chemical reactions and processes.
This impurity may also serve as a starting point for the development of new compounds with similar structures and properties, which could have potential applications in various industries, including pharmaceuticals, materials science, and environmental science.

Check Digit Verification of cas no

The CAS Registry Mumber 131944-48-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,9,4 and 4 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 131944-48:
(8*1)+(7*3)+(6*1)+(5*9)+(4*4)+(3*4)+(2*4)+(1*8)=124
124 % 10 = 4
So 131944-48-4 is a valid CAS Registry Number.

131944-48-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name (E/Z)-FK-506 26,28-Allylic Ester Rearrangement Impurity

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:131944-48-4 SDS

131944-48-4Relevant academic research and scientific papers

THERMAL REARRANGEMENT OF THE IMMUNOSUPPRESSANT FK-506

Ok, H.,Arison, B. H.,Ball, R. G.,Beatti, T. R.,Fisher, M. H.,Wyvratt, M. J.

, p. 6477 - 6480 (2007/10/02)

Treatment of FK-506 in xylene at reflux results in a sigmatropic rearrangement of the allylic ester portion of the molecule to give a new ring expanded macrolide.

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